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用激光多普勒血流仪研究人体鼻黏膜的过敏反应。

Allergic reaction of the human nasal mucosa studied with laser Doppler flowmetry.

作者信息

Juliusson S, Bende M

出版信息

Clin Allergy. 1987 Jul;17(4):301-5. doi: 10.1111/j.1365-2222.1987.tb02018.x.

DOI:10.1111/j.1365-2222.1987.tb02018.x
PMID:2957119
Abstract

The laser Doppler flowmeter is a new instrument that reflects a different physiological parameter other than rhinomanometry for examining the vascular bed of the nasal mucosa. Mucosal blood flow in allergic rhinitis may be an important, but so far little studied, factor. Laser Doppler flowmetry was used to study nasal mucosal microcirculation in seven asymptomatic patients with allergic rhinitis. Topical provocation with birch pollen extract showed a statistically significant dose-dependent increase in blood flow. The method seems useful as an in-vivo model for studying allergic rhinitis.

摘要

激光多普勒血流仪是一种新型仪器,它反映的是与鼻测压法不同的生理参数,用于检查鼻黏膜的血管床。变应性鼻炎中的黏膜血流可能是一个重要因素,但迄今为止研究较少。使用激光多普勒血流仪对7例无症状变应性鼻炎患者的鼻黏膜微循环进行了研究。用桦树花粉提取物进行局部激发试验显示,血流量呈剂量依赖性显著增加。该方法似乎是一种研究变应性鼻炎的有用的体内模型。

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Allergic reaction of the human nasal mucosa studied with laser Doppler flowmetry.用激光多普勒血流仪研究人体鼻黏膜的过敏反应。
Clin Allergy. 1987 Jul;17(4):301-5. doi: 10.1111/j.1365-2222.1987.tb02018.x.
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Priming effect of a birch pollen season studied with laser Doppler flowmetry in patients with allergic rhinitis.采用激光多普勒血流仪研究桦树花粉季节对过敏性鼻炎患者的激发效应。
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[Laser Doppler flowmetry for evaluation of nasal mucosa microcirculation].[用于评估鼻黏膜微循环的激光多普勒血流仪]
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引用本文的文献

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Pilot Study of Laser Doppler Measurement of Flow Variability in the Microcirculation of the Palatal Mucosa.腭黏膜微循环中血流变异性的激光多普勒测量的初步研究。
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2
Mediation of prolonged increases in nasal mucosal blood flow by calcitonin gene-related peptide (CGRP).
J Clin Immunol. 1990 Nov;10(6):304-10. doi: 10.1007/BF00917475.