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脑性瘫痪中非传染性疾病的风险、负担和管理:范围综述。

The risk, burden, and management of non-communicable diseases in cerebral palsy: a scoping review.

机构信息

College of Health and Life Sciences, Brunel University, London, UK.

Department of Epidemiology and Public Health Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.

出版信息

Dev Med Child Neurol. 2018 Aug;60(8):753-764. doi: 10.1111/dmcn.13737. Epub 2018 Mar 24.

Abstract

AIM

To examine the risk, burden, and management of non-communicable diseases (NCDs) among people with cerebral palsy (CP).

METHOD

Databases (Ovid MEDLINE, Embase Ovid, CINAHL Plus) were systematically searched up to August 2017. Data on the prevalence of risk factors for, and the burden and management of, cardiovascular diseases, diabetes, cancers, and respiratory diseases were extracted.

RESULTS

Thirty-six studies that examined the prevalence of risk factors among people with CP were identified. There was inconsistent evidence that people with CP had higher prevalence of metabolic risk factors such as hypertension, hyperlipidaemia, and obesity, but strong evidence that they participated in low levels of physical activity, compared with people without CP. Seven studies reported on the burden of NCDs. Adults with CP had a higher risk of NCDs, including stroke, chronic obstructive pulmonary disease, and other heart conditions, and death due to NCDs, including cancers, chronic obstructive pulmonary disease, stroke, and ischaemic heart disease, compared with the general population. Only one study reported on the management of NCD, specifically the uptake of breast cancer screening among females.

INTERPRETATION

The burden of NCDs is higher among adults with CP compared with the general population. Further research is required to determine the prevalence of metabolic risk factors and management of NCDs among people with CP.

WHAT THIS PAPER ADDS

Adults with cerebral palsy (CP) have an increased risk of non-communicable diseases (NCDs) and increased risk of death because of NCDs. Evidence is inconsistent about the elevated prevalence of metabolic risk factors for NCDs. Evidence is consistent that people with CP participate in reduced physical activity. Only one study reported on management of NCD among people with CP. Available evidence suggests people with CP are less likely to receive preventive medicine.

摘要

目的

研究脑瘫患者(CP)的非传染性疾病(NCD)风险、负担和管理。

方法

系统检索了截至 2017 年 8 月的数据库(Ovid MEDLINE、Embase Ovid、CINAHL Plus)。提取心血管疾病、糖尿病、癌症和呼吸系统疾病的危险因素流行率、负担和管理数据。

结果

确定了 36 项研究,这些研究检查了 CP 患者的危险因素流行率。有不一致的证据表明 CP 患者的代谢危险因素(如高血压、高血脂和肥胖)的患病率较高,但有强有力的证据表明,与无 CP 的患者相比,他们的身体活动水平较低。有 7 项研究报告了 NCD 的负担。与一般人群相比,CP 成年人患 NCD 的风险更高,包括中风、慢性阻塞性肺疾病和其他心脏疾病,以及 NCD 导致的死亡,包括癌症、慢性阻塞性肺疾病、中风和缺血性心脏病。只有一项研究报告了 NCD 的管理,特别是女性乳腺癌筛查的参与率。

解释

与一般人群相比,CP 成年人的 NCD 负担更高。需要进一步研究来确定 CP 患者代谢危险因素的流行率和 NCD 的管理。

本文增添内容

脑瘫患者(CP)患非传染性疾病(NCD)的风险增加,且因 NCD 而死亡的风险增加。关于 NCD 的代谢危险因素患病率的证据不一致。有证据表明 CP 患者的身体活动参与度降低。只有一项研究报告了 CP 患者的 NCD 管理情况。现有证据表明 CP 患者接受预防医学的可能性较低。

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