Magouliotis D E, Tasiopoulou V S, Tzovaras G
Department of Surgery, University Hospital of Larissa, Larissa, Greece.
Clin Obes. 2018 Jun;8(3):159-169. doi: 10.1111/cob.12246. Epub 2018 Mar 24.
We aim to review the available literature on morbidly obese patients treated with one anastomosis gastric bypass (OAGB) or Roux-en-Y gastric bypass (RYGB) in order to compare the clinical outcomes of the two methods. A literature search was performed in PubMed, Cochrane library and Scopus, in accordance with the PRISMA guidelines. Twelve studies met the inclusion criteria (7452 patients). OAGB was associated with shorter mean operative time. The length of hospital stay was comparable between the two procedures. The incidence of leaks, marginal ulcer, dumping, bowel obstruction, revisions and mortality was similar between the two approaches. The incidence of malnutrition was increased in patients treated with OAGB, while the incidence of internal hernia and bowel obstruction was greater in the RYGB group. In addition, the percentage excess weight loss at 1, 2 and 5 years post-operatively was greater for the OAGB group. The rate of type 2 diabetes remission was greater in the OAGB group. The rate of hypertension and dyslipidemia remission was also similar between OAGB and RYGB. Randomized controlled trials, comparing RYGB to OAGB, are necessary to further assess their clinical outcomes.
我们旨在回顾关于接受单吻合口胃旁路术（OAGB）或Roux-en-Y胃旁路术（RYGB）治疗的病态肥胖患者的现有文献，以比较这两种方法的临床结果。根据PRISMA指南，在PubMed、Cochrane图书馆和Scopus中进行了文献检索。12项研究符合纳入标准（7452例患者）。OAGB与较短的平均手术时间相关。两种手术的住院时间相当。两种方法之间渗漏、边缘溃疡、倾倒综合征、肠梗阻、翻修手术和死亡率的发生率相似。接受OAGB治疗的患者营养不良发生率增加，而RYGB组内疝和肠梗阻的发生率更高。此外，OAGB组术后1年、2年和5年的超重减轻百分比更高。OAGB组2型糖尿病缓解率更高。OAGB和RYGB之间高血压和血脂异常的缓解率也相似。有必要进行比较RYGB和OAGB的随机对照试验，以进一步评估它们的临床结果。
