Smith Molly Housley, Cohen Donald M, Bhattacharyya Indraneel, Islam Nadim M, Kashtwari Deeba
Department of Oral and Maxillofacial Pathology, University of Kentucky College of Dentistry, Lexington, KY, USA.
Department of Oral and Maxillofacial Diagnostic Sciences, University of Florida College of Dentistry Gainesville, FL, USA.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 Oct;126(4):e220-e227. doi: 10.1016/j.oooo.2018.02.011. Epub 2018 Feb 28.
Radiculomegaly, or root gigantism, is a rare dental abnormality with important clinical implications. It is highly specific for oculo-facio-cardio-dental (OFCD) syndrome, which places dentists at the forefront of diagnosis of this syndrome. Only 1 case of nonsyndromic radiculomegaly has been reported in the literature since the description of OFCD syndrome in 1996. We present the second confirmed, nonsyndromic/nonfamilial case and review the literature for dental treatments in patients with this dental finding.
A review of the English language literature was performed in PubMed for patients with radiculomegaly or OFCD syndrome. Teeth affected by radiculomegaly, gender, orodental findings, presence of OFCD syndrome, and dental treatment methods were recorded.
Sixty-seven cases of radiculomegaly and 92 cases of OFCD syndrome were found in the literature. Only 1 confirmed case of nonsyndromic/nonfamilial radiculomegaly had been reported previously. Ten reports described dental treatment or treatment plan details, and even fewer included specific methods.
Because dental anomalies, especially radiculomegaly, are a primary feature of OFCD syndrome, dentists should be aware of the clinical and radiographic features. Radiculomegaly poses a distinct challenge to dentists, and reports of dental therapy provided to these patients are sparse. Early diagnosis of the syndrome may prevent dental challenges and improve prognosis.
神经根粗大，或根巨症，是一种罕见的牙齿异常，具有重要的临床意义。它是眼-面-心-牙（OFCD）综合征的高度特异性表现，这使得牙医处于该综合征诊断的前沿。自1996年OFCD综合征被描述以来，文献中仅报道了1例非综合征性神经根粗大病例。我们报告第二例确诊的非综合征性/非家族性病例，并回顾文献中针对有此牙齿表现患者的牙科治疗方法。
在PubMed中对英文文献进行检索，查找患有神经根粗大或OFCD综合征的患者。记录受神经根粗大影响的牙齿、性别、口腔牙齿表现、OFCD综合征的存在情况以及牙科治疗方法。
文献中发现67例神经根粗大病例和92例OFCD综合征病例。此前仅报道过1例确诊的非综合征性/非家族性神经根粗大病例。有10篇报告描述了牙科治疗或治疗计划细节，包含具体方法的报告更少。
由于牙齿异常，尤其是神经根粗大，是OFCD综合征的主要特征，牙医应了解其临床和影像学特征。神经根粗大给牙医带来了独特的挑战，且针对这些患者的牙科治疗报告稀少。该综合征的早期诊断可能预防牙科问题并改善预后。
