Gasser B, Philippe E
J Gynecol Obstet Biol Reprod (Paris). 1987;16(4):443-9.
The abdominal wall of five fetuses suffering from the Prune-Belly syndrome and four others that had abdominal distension without enlargement of the bladder were studied histologically. This showed that there was no specific character to the abdominal wall defect classically described in the Prune-Belly syndrome. All the same, the results emphasize the importance of the teratogenic action of distension on the muscle growth in the abdominal wall as time goes on. This abdominal distension, if it starts early enough, lasts long and is severe can lead to changes that can progress as far as aplasia, or a lesser fault in development so that in some cases there may be no major abnormality in the abdominal wall.
对五名患有梅干腹综合征的胎儿以及另外四名有腹部膨胀但膀胱未增大的胎儿的腹壁进行了组织学研究。结果表明，梅干腹综合征中经典描述的腹壁缺陷并无特异性特征。尽管如此，研究结果强调了随着时间推移，膨胀对腹壁肌肉生长的致畸作用的重要性。这种腹部膨胀，如果开始得足够早、持续时间长且程度严重，可能会导致发育异常，严重的可发展为发育不全，或程度较轻的发育缺陷，以至于在某些情况下腹壁可能没有重大异常。
