Campos-Muñoz Lucía, López-De Lara Diego, Rodríguez-Rojo Marina L, Conde-Taboada Alberto, López-Bran Eduardo
Department of Dermatology, Hospital Clínico San Carlos, Madrid, Spain.
Department of Pediatrics, Hospital Clínico San Carlos, Madrid, Spain.
Pediatr Dermatol. 2018 May;35(3):e155-e158. doi: 10.1111/pde.13448. Epub 2018 Mar 25.
We describe the difficulties of treating acne in a series of female-to-male transgender adolescents, including concerns about potential hepatotoxicity with concomitant use of testosterone with isotretinoin or tetracyclines. Acne is a foreseeable adverse effect of testosterone treatment in transgender adolescents, so monitoring for acne is advised. The treatment of acne in transgender adolescents is important given that severe acne and transgenderism are associated with higher rates of depression and suicide.
我们描述了一系列女性向男性转变的青少年痤疮治疗的困难，包括担心睾酮与异维A酸或四环素同时使用时可能产生的肝毒性。痤疮是变性青少年睾酮治疗可预见的不良反应，因此建议对痤疮进行监测。鉴于严重痤疮和性别认同障碍与更高的抑郁和自杀率相关，变性青少年痤疮的治疗很重要。
