McLaughlin D S, Diamond M P, Daniell J F, Martin D C, Feste J
Microsurgery. 1987;8(2):99-102. doi: 10.1002/micr.1920080214.
A prospective multicenter study was undertaken by the Intraabdominal Laser Study Group to assess the type and extent of ovarian adhesions formed following incisional ovarian surgery performed as part of a fertility-promoting procedure with the aid of the carbon dioxide laser. Ovarian healing with subsequent adhesion formation was evaluated by early second-look laparoscopy. Two suture closing materials were used--Surgilon (siliconized braided nylon, David and Geck, Wayne, NJ) and Vicryl (polyglactin 910, Ethicon, Somerville, NJ). Sixty-five ovaries were evaluated in 37 patients with subsequent adhesions found in 37% (18/49) of the Surgilon-closed ovaries and in 94% (15/16) of the Vicryl-closed ovaries. The adhesions were filmy in 83% (15/18) of the Surgilon group and 47% (7/15) of the Vicryl group. Dense/vascular adhesions were found in 17% (3/18) of the Surgilon group and 53% (8/15) of the Vicryl group. The subsequent conception rates were 68% (17/25) in the Surgilon group and 33% (4/12) in the Vicryl group, although the small number of patients and multitude of infertility factors made pregnancy rate comparisons difficult. One of the authors noted lack of tensile strength in the Vicryl-closed ovaries within 12 weeks postlaser laparotomy, which led to incisional dehiscence during laparoscopic lysis of ovarian adhesions. From this preliminary study, it is concluded that additional data are needed to more fully resolve the debate on whether absorbable or nonabsorbable suture is preferred for ovarian infertility surgery.
腹腔内激光研究小组开展了一项前瞻性多中心研究,以评估在借助二氧化碳激光进行的促进生育手术中,切开卵巢手术后形成的卵巢粘连的类型和程度。通过早期二次腹腔镜检查评估卵巢愈合及随后粘连的形成情况。使用了两种缝合封闭材料——Surgilon(硅化编织尼龙,大卫和壁虎公司,新泽西州韦恩市)和薇乔(聚乙醇酸910,强生公司,新泽西州萨默维尔市)。对37例患者的65个卵巢进行了评估,结果发现,使用Surgilon缝合封闭的卵巢中有37%(18/49)出现了粘连,而使用薇乔缝合封闭的卵巢中有94%(15/16)出现了粘连。Surgilon组中83%(15/18)的粘连为薄膜状,薇乔组中47%(7/15)的粘连为薄膜状。Surgilon组中17%(3/18)的粘连为致密/血管性粘连,薇乔组中53%(8/15)的粘连为致密/血管性粘连。Surgilon组随后的受孕率为68%(17/25),薇乔组为33%(4/12),不过患者数量较少且不孕因素众多,使得受孕率比较困难。其中一位作者指出,激光剖腹术后12周内,薇乔缝合封闭的卵巢缺乏抗张强度,这导致在腹腔镜下松解卵巢粘连时出现切口裂开。从这项初步研究可以得出结论,需要更多数据才能更全面地解决关于卵巢不孕手术中使用可吸收缝线还是不可吸收缝线更优的争论。