Diamond M P, Daniell J F, Martin D C, Feste J, Vaughn W K, McLaughlin D S
Fertil Steril. 1984 Nov;42(5):717-23. doi: 10.1016/s0015-0282(16)48196-3.
It has been suggested that the carbon dioxide (CO2) laser, by virtue of its hypothetical capabilities for precise incisions, minimization of tissue handling and bleeding, and shortened operating time, may improve the success rate of gynecologic infertility surgery. To assess this hypothesis, a multicenter prospective study was performed to assess tubal patency and adhesion formation at early second-look laparoscopy after intraabdominal laser surgery. Procedures performed included salpingoneostomy, fimbrioplasty, lysis of adhesions, vaporization of endometriosis, and ovarian wedge resection. The results were compared with those of another multicenter prospective study that utilized nonlaser reconstructive pelvic surgery. Use of the CO2 laser was found to result in a greater tubal patency rate at the time of the second-look procedure. Adhesions present at the time of the second-look procedure were reduced from initial presentation at most sites; however, nonlaser infertility surgery appeared to have equal or greater efficacy in the prevention of adhesion formation at most sites. Thus, the CO2 laser does not appear to be a panacea for the treatment of tuboperitoneal causes of infertility. Pregnancy rates following intraabdominal use of the CO2 laser remain to be established.
有人提出,二氧化碳(CO2)激光凭借其在精确切割、减少组织操作和出血以及缩短手术时间方面的假设能力,可能会提高妇科不孕症手术的成功率。为了评估这一假设,进行了一项多中心前瞻性研究,以评估腹腔内激光手术后早期二次腹腔镜检查时的输卵管通畅情况和粘连形成情况。所进行的手术包括输卵管造口术、伞端成形术、粘连松解术、子宫内膜异位症汽化术和卵巢楔形切除术。将结果与另一项使用非激光重建性盆腔手术的多中心前瞻性研究的结果进行了比较。发现在二次检查时,使用CO2激光可使输卵管通畅率更高。在大多数部位,二次检查时出现的粘连较初次检查时有所减少;然而,在大多数部位,非激光不孕症手术在预防粘连形成方面似乎具有同等或更高的疗效。因此,CO2激光似乎并非治疗输卵管腹腔性不孕症的万灵药。腹腔内使用CO2激光后的妊娠率仍有待确定。