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保险类型对亚裔美国人和非西班牙裔白人肺癌患者就诊时的分期、治疗和生存的影响。

The influence of insurance type on stage at presentation, treatment, and survival between Asian American and non-Hispanic White lung cancer patients.

机构信息

Department of Thoracic Surgery, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1023 Annenberg Building, 7-56, New York City, 10029, New York.

Department of Surgery, Faculty of Medicine, Chiang Mai University, 110 Intawaroros Road, Chiang Mai, 50200, Thailand.

出版信息

Cancer Med. 2018 May;7(5):1612-1629. doi: 10.1002/cam4.1331. Epub 2018 Mar 25.

Abstract

The effect of insurance type on lung cancer diagnosis, treatment, and survival in Asian patients living in the United States is still under debate. We have analyzed this issue using the Surveillance, Epidemiology, and End Results database. There were 102,733 lung cancer patients age 18-64 years diagnosed between 2007 and 2013. Multilevel regression analysis was performed to identify the association between insurance types, stage at diagnosis, treatment modalities, and overall mortality in Asian and non-Hispanic White (NHW) patients. Clinical characteristics were significantly different between Asian and NHW patients, except for gender. Asian patients were more likely to present with advanced disease than NHW patients (OR = 1.12, 95% CI = 1.06-1.19). Asian patients with non-Medicaid insurance underwent lobectomy more than NHW patients with Medicaid or uninsured; were more likely to undergo mediastinal lymph node evaluation (MLNE) (OR = 1.98, 95% CI = 1.72-2.28) and cancer-directed surgery and/or radiation therapy (OR = 1.41, 95% CI = 1.20-1.65). Asian patients with non-Medicaid insurance had the best overall survival. Uninsured or Medicaid-covered Asian patients were more likely to be diagnosed with advanced disease, less likely to undergo MLNE and cancer-directed treatments, and had shorter overall survival than their NHW counterpart.

摘要

在美国居住的亚洲患者的保险类型对肺癌诊断、治疗和生存的影响仍存在争议。我们使用监测、流行病学和最终结果数据库分析了这个问题。2007 年至 2013 年间诊断出 102733 例年龄在 18-64 岁之间的肺癌患者。采用多层次回归分析确定了亚洲患者和非西班牙裔白人(NHW)患者之间的保险类型、诊断时的分期、治疗方式以及总体死亡率之间的关联。亚洲患者和 NHW 患者之间的临床特征存在显著差异,但性别除外。与 NHW 患者相比,亚洲患者更有可能患有晚期疾病(OR=1.12,95%CI=1.06-1.19)。有非医疗补助保险的亚洲患者比有医疗补助或无保险的 NHW 患者更有可能接受肺叶切除术;更有可能接受纵隔淋巴结评估(MLNE)(OR=1.98,95%CI=1.72-2.28)和癌症定向手术和/或放射治疗(OR=1.41,95%CI=1.20-1.65)。有非医疗补助保险的亚洲患者的总体生存率最高。无保险或有医疗补助覆盖的亚洲患者更有可能被诊断为晚期疾病,更不可能接受 MLNE 和癌症定向治疗,并且总体生存率比他们的 NHW 对应者更短。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0a5/5943464/34ce99f67752/CAM4-7-1612-g001.jpg

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