Kanecki Krzysztof, Nitsch-Osuch Aneta, Goryński Paweł, Bogdan Magdalena, Tarka Patryk, Tyszko Piotr Zbigniew
Department of Social Medicine and Public Health, Medical University of Warsaw, Warsaw, Poland.
National Institute of Public Health - National Institute of Hygiene, Warsaw, Poland.
Ann Agric Environ Med. 2018 Mar 14;25(1):182-185. doi: 10.26444/aaem/81080. Epub 2018 Feb 12.
Paget's disease (PDB) is a focal disorder of bone remodeling that occurs commonly in older people with decreasing prevalence reported in European countries. This disease is most often asymptomatic, but it can cause a variety of medical complications resulting in considerable morbidity and reduced quality of life. There is little information regarding the epidemiology of PDB in Poland. To the best of the authors' knowledge, this is the first large epidemiological analysis of this disease in Poland.
The aim of this study was to analyze factors that may be related to the PDB epidemiology among hospitalized patients in Poland.
The analysis was conducted on the basis of population-based administrative data, taken from a Polish hospital morbidity study carried out by the National Institute of Public Health between January 2008 - December 2014.
Analyzed data covered 662 hospitalization records. The final study sample comprised 94 (41.8%) male and 131 (58.2%) female patients with first-time hospitalizations for PDB, with a significant predominance of females (P<0.02), and the predominance of patients living in urban (73%) than in rural areas (27%), P<0.001. The average age of the sample was 56.8 years (CI: 54.3-59.3; SD 18.8; range 1-93 years). The number of PDB cases hospitalized in Poland significantly decreased during the analyzed period of time.
PDB is a rare disease with decreasing trends observed among hospitalized patients in Poland. The study results may suggest the existence of environmental risk factors for the development of PDB.
佩吉特病（PDB）是一种局限性骨重塑疾病，常见于老年人，在欧洲国家的发病率呈下降趋势。这种疾病通常无症状，但可导致多种医学并发症，从而造成相当大的发病率并降低生活质量。关于波兰佩吉特病的流行病学信息很少。据作者所知，这是波兰对该疾病进行的首次大型流行病学分析。
本研究旨在分析波兰住院患者中可能与佩吉特病流行病学相关的因素。
该分析基于以人群为基础的行政数据，数据取自国家公共卫生研究所于2008年1月至2014年12月开展的一项波兰医院发病率研究。
分析的数据涵盖662份住院记录。最终研究样本包括94名（41.8%）首次因佩吉特病住院的男性患者和131名（58.2%）女性患者，女性占显著优势（P<0.02），且居住在城市的患者（73%）比农村地区的患者（27%）占优势，P<0.001。样本的平均年龄为56.8岁（置信区间：54.3 - 59.3；标准差18.8；范围1 - 93岁）。在分析期间，波兰因佩吉特病住院的病例数显著减少。
佩吉特病是一种罕见疾病，在波兰住院患者中呈下降趋势。研究结果可能表明存在佩吉特病发病的环境危险因素。
