Kęska Anna, Lutosławska Grażyna, Bertrandt Jerzy, Sobczak Małgorzata
Department of Biochemistry and Biology, University of Physical Education, Warsaw, Poland.
Department of Hygiene and Epidemiology, Military Institute of Hygiene and Epidemiology, Warsaw, Poland.
Ann Agric Environ Med. 2018 Mar 14;25(1):23-25. doi: 10.5604/12321966.1233562. Epub 2017 Feb 11.
Data concerning the relationship between body fat and BMD are equivocal since both positive and negative effects have been noted. Recently, the index of fat mass (IFM) representing subjects with different body fat and similar lean mass and index of lean mass (ILM) representing subjects with different lean body mass and similar body fat, have been used to evaluate body composition effect on BMD in middle-aged women. This study aimed at determination of ILM and IFM association with BMD in young men and women.
A total of 212 university students of Public Health (125 women and 87 men) participated in the study. Body composition was determined by the bioelectrical impedance method (BIA) using BC 418 MA equipment (Tanita Co., Japan). Fat mass and fat free mass were used to calculate ILM and IFM. Bone mineral density was measured on the wrist of the non-dominant hand using the DEXA method and EXA 3000 equipment (HFS Ltd., Korea). BMD was evaluated using Z-score, with values lower than -2.0 indicating inadequate BMD for subject chronological age.
Exclusively in women, IFM was markedly and positively correlated with Z-score (r=0.366, P<0.001). In both genders, a significant relationship was found between ILM and Z-scores (r=0.420; p<0.001 and r=0.220; p<0.02 in men and women, respectively). Women with lower than median IFM but similar ILM, were characterized by significantly lower Z-scores vs. women with higher IFM (-1.016 vs. -0.512; p<0.001). Irrespective of gender, participants with higher ILM but similar IFM, were characterized by markedly higher Z-score vs. their counterparts with low ILM.
The use of IFM and ILM in the present study, allowed the observation that in young adults lean body mass was associated with BMD, regardless of gender, while fat mass is significant for bone mineral density only in women.
由于已观察到体脂与骨密度（BMD）之间存在正向和负向影响，二者关系的数据并不明确。最近，代表不同体脂和相似瘦体重个体的脂肪量指数（IFM）以及代表不同瘦体重和相似体脂个体的瘦体重指数（ILM），已被用于评估中年女性体成分对骨密度的影响。本研究旨在确定年轻男性和女性中ILM和IFM与骨密度的关联。
共有212名公共卫生专业大学生（125名女性和87名男性）参与了本研究。使用BC 418 MA设备（日本Tanita公司）通过生物电阻抗法（BIA）测定体成分。用脂肪量和去脂体重计算ILM和IFM。使用双能X线吸收法（DEXA）和EXA 3000设备（韩国HFS有限公司）测量非优势手手腕的骨密度。用Z评分评估骨密度，Z值低于-2.0表明受试者骨密度相对于其实际年龄不足。
仅在女性中，IFM与Z评分显著正相关（r = 0.366，P < 0.001）。在男性和女性中，均发现ILM与Z评分之间存在显著关系（男性r = 0.420，P < 0.001；女性r = 0.220，P < 0.02）。IFM低于中位数但ILM相似的女性，其Z评分显著低于IFM较高的女性（-1.016对-0.512；P < 0.001）。无论性别如何，ILM较高但IFM相似 的参与者，其Z评分显著高于ILM较低的对应者。
在本研究中使用IFM和ILM发现，在年轻人中，无论性别，瘦体重均与骨密度相关，但脂肪量仅对女性的骨密度有显著影响。
