Skaudickas Darijus, Lenčiauskas Povilas, Skaudickas Augustas, Undžytė Greta
Lithuania Medical Academy, Lithuanian University of Health Sciences, Eiveniu 2, 50161, Kaunas, Lithuania.
Open Med (Wars). 2023 Oct 28;18(1):20230832. doi: 10.1515/med-2023-0832. eCollection 2023.
Chronic prostatitis (CP) is one of the diseases that reduce the quality of life (QoL) of young men. To date, there is no consensus on the management of these patients. It is essential to continue research into the treatment of CP, despite the use of various therapies, including low-energy extracorporeal shockwave therapy (ESWT). The main objective of this study is to observe and record the clinical symptomatology of patients during a 48-week follow-up period after ESWT treatment. Between 2019 and 2021, 28 patients with type IIIB CP/chronic pelvic pain syndrome were enrolled. Patients underwent ESWT once weekly for 4 weeks (3,000 individual sessions, maximum total energy flux density 0.25 mJ/mm, frequency 3 Hz). Participants were assessed at 0, 4, 12, 24, 36 and 48 weeks post-treatment using the visual analogue scale (VAS), National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI), and International Index of Erectile Function (IIEF)-5. The mean age of patients was 47.1 ± 13.7 years (range 28-4 years). The positive effect of LI-ESWT was reflected in improvements in VAS, NIH-CPSI, and IIEF-5 scores. Regression of patients' symptoms was observed as early as 4 weeks after treatment. The greatest progress was achieved at week 24. In addition, a slight worsening was observed at week 36 and 48, with stable progress. The treatment significantly improved the QoL of the patients, with the most significant improvement in the VAS score. In conclusion, this treatment approach is safe, most effective in the first 6 months. Thereafter, the efficacy of the treatment diminishes, but is sustained over a longer period.
慢性前列腺炎(CP)是降低青年男性生活质量(QoL)的疾病之一。迄今为止,对于这些患者的管理尚无共识。尽管使用了包括低能量体外冲击波疗法(ESWT)在内的各种疗法,但继续开展CP治疗的研究至关重要。本研究的主要目的是观察并记录ESWT治疗后48周随访期内患者的临床症状。在2019年至2021年期间,纳入了28例IIIB型CP/慢性盆腔疼痛综合征患者。患者每周接受1次ESWT治疗,共4周(3000次单次治疗,最大总能量通量密度0.25 mJ/mm,频率3 Hz)。在治疗后0、4、12、24、36和48周使用视觉模拟量表(VAS)、美国国立卫生研究院慢性前列腺炎症状指数(NIH-CPSI)和国际勃起功能指数(IIEF)-5对参与者进行评估。患者的平均年龄为47.1±13.7岁(范围28 - 74岁)。低强度体外冲击波疗法(LI-ESWT)的积极作用体现在VAS、NIH-CPSI和IIEF-5评分的改善上。早在治疗后4周就观察到患者症状的消退。在第24周取得了最大进展。此外,在第36周和48周观察到轻微恶化,但进展稳定。该治疗显著改善了患者的生活质量,VAS评分改善最为显著。总之,这种治疗方法是安全的,在前6个月最有效。此后,治疗效果逐渐减弱,但能在较长时间内维持。