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肉毒杆菌毒素与拇指掌指关节桡侧副韧带重建

Botox and Thumb MCP Radial Collateral Ligament Reconstruction.

作者信息

Cates Robert A, Brault Jeffrey S, Kakar Sanjeev

机构信息

Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.

Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, Minnesota.

出版信息

J Wrist Surg. 2018 Apr;7(2):156-159. doi: 10.1055/s-0037-1604396. Epub 2017 Jul 24.

DOI:10.1055/s-0037-1604396
PMID:29576922
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5864494/
Abstract

We report the use of botulinum toxin to aid in the treatment of chronic radial collateral ligament insufficiency of the thumb.  Treatment included autograft tendon reconstruction and cast immobilization. Six weeks postoperatively, prior to hand therapy, the patient underwent an ultrasound-guided botulinum neurotoxin A injection into the adductor pollicis muscle to negate its deforming forces on the reconstruction. The patient made an excellent recovery and 1 year postoperatively was pain free and had a stable radial collateral ligament (RCL) upon examination.  The outcomes of RCL repair and reconstruction are unpredictable, in part, due to the strong opposing forces of the adductor pollicis.  The use of Botox injection may enhance the outcomes of RCL repair or reconstruction by neutralizing the deforming forces of the adductor muscle.

摘要

我们报告了使用肉毒杆菌毒素辅助治疗拇指桡侧副韧带慢性损伤的情况。治疗方法包括自体肌腱重建和石膏固定。术后六周,在进行手部治疗之前,患者接受了超声引导下向拇收肌注射A型肉毒杆菌神经毒素,以消除其对重建部位的变形力。患者恢复良好,术后1年无痛,检查时桡侧副韧带(RCL)稳定。RCL修复和重建的结果不可预测,部分原因是拇收肌的强大对抗力。肉毒杆菌毒素注射的使用可能通过中和内收肌的变形力来提高RCL修复或重建的效果。

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本文引用的文献

1
Novel Uses for Botulinum Neurotoxin in Upper Limb Surgery.肉毒杆菌神经毒素在上肢手术中的新用途。
J Hand Microsurg. 2015 Jun;7(1):102-3. doi: 10.1007/s12593-014-0153-3. Epub 2014 Sep 13.
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Collateral ligament injuries of the thumb metacarpophalangeal joint.拇指掌指关节侧副韧带损伤。
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Radial collateral ligament injuries of the thumb.拇指桡侧副韧带损伤
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5
Bioprotection of tendon repair: adjunctive use of botulinum toxin A in Achilles tendon repair in the rat.肌腱修复的生物保护:肉毒杆菌毒素A在大鼠跟腱修复中的辅助应用。
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6
Results of surgical treatment of acute and chronic grade III [corrected] tears of the radial collateral ligament of the thumb metacarpophalangeal joint.拇指掌指关节桡侧副韧带急性和慢性III级[校正后]撕裂的手术治疗结果
J Hand Surg Am. 2006 Jan;31(1):68-75. doi: 10.1016/j.jhsa.2005.08.013.
7
Results of zone II flexor tendon repair in children younger than age 6 years: botulinum toxin type A administration eased cooperation during the rehabilitation and improved outcome.6岁以下儿童Ⅱ区屈指肌腱修复的结果:A型肉毒杆菌毒素的应用减轻了康复过程中的配合难度并改善了预后。
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8
Botulinum toxin in clinical practice.临床实践中的肉毒杆菌毒素。
J Neurol Neurosurg Psychiatry. 2004 Jul;75(7):951-7. doi: 10.1136/jnnp.2003.034702.
9
Effects of the adductor pollicis and abductor pollicis brevis on thumb metacarpophalangeal joint laxity before and after ulnar collateral ligament reconstruction.尺侧副韧带重建前后拇内收肌和拇短展肌对拇指掌指关节松弛度的影响。
J Hand Surg Am. 2004 May;29(3):481-8. doi: 10.1016/j.jhsa.2004.01.004.
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