纳秒级脉冲电场消融肝癌激活抗肿瘤免疫反应
Activation of Anti-tumor Immune Response by Ablation of HCC with Nanosecond Pulsed Electric Field.
作者信息
Xu Xiaobo, Chen Yiling, Zhang Ruiqing, Miao Xudong, Chen Xinhua
机构信息
Collaborative Innovation Center for Diagnosis Treatment of Infectious Diseases, Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang, China.
Department of Anatomy, Tianjin Medical University, Tianjin, China.
出版信息
J Clin Transl Hepatol. 2018 Mar 28;6(1):85-88. doi: 10.14218/JCTH.2017.00042. Epub 2017 Oct 27.
Locoregional therapy is playing an increasingly important role in the non-surgical management of hepatocellular carcinoma (HCC). The novel technique of non-thermal electric ablation by nanosecond pulsed electric field has been recognized as a potential locoregional methodology for indicated HCC. This manuscript explores the most recent studies to indicate its unique anti-tumor immune response. The possible immune mechanism, termed as nano-pulse stimulation, was also analyzed.
局部区域治疗在肝细胞癌（HCC）的非手术治疗中发挥着越来越重要的作用。纳秒脉冲电场非热电消融新技术已被公认为是一种针对特定HCC的潜在局部区域治疗方法。本文探讨了最新研究以表明其独特的抗肿瘤免疫反应。还分析了被称为纳米脉冲刺激的可能免疫机制。
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