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经肛门保肛根治术治疗超低位直肠癌

[Transanal conformal resection for super low rectal cancer].

作者信息

Lou Zheng, Zhang Wei

机构信息

Department of Colorectal Surgery, Changhai Hospital, Navy Medical University, Shanghai 200433, China.

出版信息

Zhonghua Wei Chang Wai Ke Za Zhi. 2018 Mar 25;21(3):246-249.

Abstract

Intersphincteric resection(ISR) is a valuable anus-preserving operation that avoids the need for permanent stoma in patients with super low rectal cancer. Recently, with the application and promotion of ISR, the rate of anus-preservation has been greatly elevated, however, some patients following ISR had poor anal function. Based on the knowledge of anal canal anatomical features for better anal function, we propose conformal sphincter-preserving operation (CSPO) for super low rectal cancer, which is a new integrated anus-preservation procedure with total mesorectal excision (TME), coloanal anastomosis, pull through resection, anal canal dissection, local resection and natural orifice transluminal endoscopic surgery technology. CSPO includes pull through conformal resection (PTCR) and transanal conformal resection (TaCR). This article focuses on the problems about TaCR for very low rectal cancer and introduces TaCR combined with our practical experience. The indications for the TaCR operation should be according to the conventional laparoscopic surgery. In addition, the TaCR operation has its special indications: the tumor location is within 2 cm of the dental line; the tumor is well differentiation (moderately to well differentiation); the diameter of the tumor is not more than 3 cm or no more than the 1/3 circle of intestinal wall; and the depth of invasion is T1-T2. Patients with a clinical complete remission after neoadjuvant radiochemotherapy can receive TaCR. The laparoscopic five hole method is used to carry out the abdominal operation with TME technique. It is unnecessary to dissection intersphincter space. The incisional line is made according to the tumor location and shape to preserve the opposite normal rectal wall, internal sphincter and dentate line as more as possible via transanal resection. After closing the rectal stump by interrupted sutures, a circular stapler or hand suture is use to perform the anastomosis as far from the dentate line as possible. Protective loop ileostomy is performed. Postoperative complications, including anastomotic leakage, abdominal infection, and anastomotic bleeding, should be remembered. If there is any signs of these complications, intervention should be done as soon as possible.

摘要

括约肌间切除术(ISR)是一种有价值的保肛手术,可避免超低位直肠癌患者永久性造口的需要。近年来,随着ISR的应用和推广,保肛率大幅提高,但部分ISR术后患者肛门功能不佳。基于对肛管解剖特征的认识以改善肛门功能,我们提出了适用于超低位直肠癌的保形括约肌保留手术(CSPO),这是一种新的综合保肛手术,融合了全直肠系膜切除(TME)、结肠肛管吻合术、拖出式切除术、肛管解剖、局部切除术和经自然腔道内镜手术技术。CSPO包括拖出式保形切除术(PTCR)和经肛门保形切除术(TaCR)。本文重点关注TaCR治疗极低位直肠癌的相关问题,并结合我们的实践经验介绍TaCR。TaCR手术的适应证应参照传统腹腔镜手术。此外,TaCR手术有其特殊适应证:肿瘤位于齿状线2cm以内;肿瘤分化良好(中度至高度分化);肿瘤直径不超过3cm或不超过肠壁的1/3圆周;浸润深度为T1 - T2。新辅助放化疗后临床完全缓解的患者可接受TaCR。采用腹腔镜五孔法,运用TME技术进行腹部手术。无需解剖括约肌间隙。根据肿瘤位置和形状确定切口线,经肛门切除时尽可能保留相对正常的直肠壁、内括约肌和齿状线。间断缝合关闭直肠残端后,使用圆形吻合器或手工缝合进行尽可能远离齿状线的吻合。行保护性回肠造口术。应注意术后并发症,包括吻合口漏、腹腔感染和吻合口出血。若出现这些并发症的任何迹象,应尽早干预。

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