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肾移植受者阑尾切除术的手术入路、费用和并发症。

Surgical approach, cost, and complications of appendectomy in kidney transplant recipients.

机构信息

Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Department of Surgery, University of California, San Francisco, CA, USA.

出版信息

Clin Transplant. 2018 May;32(5):e13245. doi: 10.1111/ctr.13245. Epub 2018 Apr 17.

Abstract

Kidney transplant recipients (KTRs) have greater morbidity and length of stay (LOS) following certain surgical procedures than non-KTR. Given that appendectomy is one of the most common surgical procedures, we investigated differences in outcomes between 1336 KTR and 2 640 247 non-KTR postappendectomy at transplant and nontransplant centers in the United States from 2000 to 2011, using NIS data and adjusting for patient-level and hospital-level factors. Postoperative complications were identified using ICD-9 codes. Among KTR, there were no post-appendectomy in-hospital deaths, compared to a 0.2% in non-KTR (P = .5). Overall complications were similar among KTR and non-KTR (17.0% vs 11.6%; aOR: 1.12 ). LOS and costs were greater for KTR compared to non-KTR (LOS ratio 1.31 ; cost ratio 1.17 ). Only 44.8% of KTR had laparoscopic approach compared to 54.5% of non-KTR, but had similar complication rates (10.6 vs 8.7%, P = .5). When treated at transplant centers, KTR had similar complications (aOR 0.79 ), but longer LOS (ratio 1.37 ) and greater hospital-associated costs (ratio 1.29 ) than non-KTR. Conversely, at nontransplant centers, KTR and non-KTR had similar complications (aOR 1.23 ), LOS (ratio 0.96 ), and cost (ratio 1.01 ). Contrary to other procedures, KTR did not constitute a high-risk group for patients undergoing appendectomy.

摘要

肾移植受者(KTR)在接受某些手术后的发病率和住院时间(LOS)高于非 KTR。鉴于阑尾切除术是最常见的手术之一,我们调查了 2000 年至 2011 年期间美国移植和非移植中心的 1336 名 KTR 和 2640247 名非 KTR 阑尾切除术后的结果差异,使用 NIS 数据并调整了患者水平和医院水平的因素。术后并发症使用 ICD-9 代码识别。在 KTR 中,手术后院内无死亡病例,而非 KTR 为 0.2%(P =.5)。KTR 和非 KTR 的总体并发症相似(17.0%对 11.6%;aOR:1.12)。与非 KTR 相比,KTR 的 LOS 和费用更高(LOS 比 1.31;成本比 1.17)。只有 44.8%的 KTR 采用了腹腔镜方法,而非 KTR 为 54.5%,但并发症发生率相似(10.6%对 8.7%,P =.5)。在移植中心治疗时,KTR 的并发症相似(aOR 0.79),但 LOS 更长(比值 1.37),医院相关费用更高(比值 1.29)。相反,在非移植中心,KTR 和非 KTR 的并发症(aOR 1.23)、LOS(比值 0.96)和成本(比值 1.01)相似。与其他手术不同,KTR 并不是接受阑尾切除术患者的高风险人群。

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