Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Department of Surgery, University of California, San Francisco, CA, USA.
Clin Transplant. 2018 May;32(5):e13245. doi: 10.1111/ctr.13245. Epub 2018 Apr 17.
Kidney transplant recipients (KTRs) have greater morbidity and length of stay (LOS) following certain surgical procedures than non-KTR. Given that appendectomy is one of the most common surgical procedures, we investigated differences in outcomes between 1336 KTR and 2 640 247 non-KTR postappendectomy at transplant and nontransplant centers in the United States from 2000 to 2011, using NIS data and adjusting for patient-level and hospital-level factors. Postoperative complications were identified using ICD-9 codes. Among KTR, there were no post-appendectomy in-hospital deaths, compared to a 0.2% in non-KTR (P = .5). Overall complications were similar among KTR and non-KTR (17.0% vs 11.6%; aOR: 1.12 ). LOS and costs were greater for KTR compared to non-KTR (LOS ratio 1.31 ; cost ratio 1.17 ). Only 44.8% of KTR had laparoscopic approach compared to 54.5% of non-KTR, but had similar complication rates (10.6 vs 8.7%, P = .5). When treated at transplant centers, KTR had similar complications (aOR 0.79 ), but longer LOS (ratio 1.37 ) and greater hospital-associated costs (ratio 1.29 ) than non-KTR. Conversely, at nontransplant centers, KTR and non-KTR had similar complications (aOR 1.23 ), LOS (ratio 0.96 ), and cost (ratio 1.01 ). Contrary to other procedures, KTR did not constitute a high-risk group for patients undergoing appendectomy.
肾移植受者(KTR)在接受某些手术后的发病率和住院时间(LOS)高于非 KTR。鉴于阑尾切除术是最常见的手术之一,我们调查了 2000 年至 2011 年期间美国移植和非移植中心的 1336 名 KTR 和 2640247 名非 KTR 阑尾切除术后的结果差异,使用 NIS 数据并调整了患者水平和医院水平的因素。术后并发症使用 ICD-9 代码识别。在 KTR 中,手术后院内无死亡病例,而非 KTR 为 0.2%(P =.5)。KTR 和非 KTR 的总体并发症相似(17.0%对 11.6%;aOR:1.12)。与非 KTR 相比,KTR 的 LOS 和费用更高(LOS 比 1.31;成本比 1.17)。只有 44.8%的 KTR 采用了腹腔镜方法,而非 KTR 为 54.5%,但并发症发生率相似(10.6%对 8.7%,P =.5)。在移植中心治疗时,KTR 的并发症相似(aOR 0.79),但 LOS 更长(比值 1.37),医院相关费用更高(比值 1.29)。相反,在非移植中心,KTR 和非 KTR 的并发症(aOR 1.23)、LOS(比值 0.96)和成本(比值 1.01)相似。与其他手术不同,KTR 并不是接受阑尾切除术患者的高风险人群。