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覆膜支架在主动脉缩窄和动脉导管未闭同期治疗中的应用。

Use of covered stents in simultaneous management of coarctation of the aorta and patent ductus arteriosus.

作者信息

Hekim Yılmaz Emine, Bulut Mustafa Orhan, Küçük Mehmet, Yücel İlker Kemal, Erdem Abdullah, Çelebi Ahmet

机构信息

Department of Pediatric Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital; İstanbul-Turkey.

出版信息

Anatol J Cardiol. 2018 Apr;19(4):332-336. doi: 10.14744/AnatolJCardiol.2018.61257. Epub 2018 Mar 21.

Abstract

OBJECTIVE

To report clinical and procedural characteristics of twelve patients who received a covered stent for the treatment of aortic coarctation and concurrent patent ductus arteriosus (PDA).

METHODS

A single center database was retrospectively evaluated to obtain data of patients with combined aortic coarctation and PDA. We selected patients in whom a covered stent was used for the treatment of both pathologies. The stent length was chosen so as to cover the entire length of the lesion from healthy to healthy tissue and also cover the ampulla of PDA.

RESULTS

The median age of the patients was 15 (range, 6.5-35) years. The diameter of the coarctated segment increased from a median of 8.4 (range, 2.6-10.8) mm to 16 (range, 9-24) mm (p<0.005), whereas the pressure gradient decreased from a median of 43 (range, 10-71) mm Hg to 0 (range, 0-8) mm Hg (p<0.005). Fourteen covered stents were used for 12 patients. Following deployment, seven stents were flared with larger and low-pressure balloons because of the gap between the distal end of the stent and the poststenotic dilated segment of the aorta, which caused residual PDA shunts and/or instability of the stent. After the procedure, no residual PDA shunt was present in any patient.

CONCLUSION

To the best of our knowledge, this study includes the largest series of patients reported in literature in whom covered CP stents were used for simultaneous percutaneous treatment of coarctation and PDA. The procedure was successful and stable results were obtained during follow-up in all cases.

摘要

目的

报告12例接受覆膜支架治疗主动脉缩窄合并动脉导管未闭(PDA)患者的临床及手术特征。

方法

回顾性评估单中心数据库,以获取主动脉缩窄合并PDA患者的数据。我们选择使用覆膜支架治疗这两种病变的患者。选择支架长度以覆盖从健康组织到健康组织的整个病变长度,并覆盖PDA的壶腹部。

结果

患者的中位年龄为15岁(范围6.5 - 35岁)。缩窄段直径从中位值8.4 mm(范围2.6 - 10.8 mm)增加到16 mm(范围9 - 24 mm)(p<0.005),而压力梯度从中位值43 mmHg(范围10 - 71 mmHg)降至0 mmHg(范围0 - 8 mmHg)(p<0.005)。12例患者共使用了14个覆膜支架。植入后,由于支架远端与主动脉缩窄后扩张段之间的间隙,导致7个支架使用更大的低压球囊进行扩张,这引起了残余PDA分流和/或支架不稳定。术后,所有患者均无残余PDA分流。

结论

据我们所知,本研究纳入了文献报道中使用覆膜CP支架同时经皮治疗缩窄和PDA的最大系列患者。该手术成功,所有病例随访期间均获得稳定结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b11a/5998845/9e56a8fada7a/AJC-19-232-g001.jpg

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