Department of Medicine, School of Medicine, University of California, San Francisco, San Francisco, California.
Semin Respir Crit Care Med. 2018 Apr;39(2):255-268. doi: 10.1055/s-0037-1615801. Epub 2018 Mar 26.
Lung transplantation (LT) has the potential to extend survival and improve quality of life (QOL) for patients suffering from end-stage lung disease. This review describes the many ways in which success can be defined in LT. It evaluates the improvements in survival outcomes after LT over time, and describes ways to measure the success of LT other than survival after transplantation. It also addresses the importance of patient-centered outcomes and how improvements in health-related quality of life (HRQL) are pivotal to defining success within LT.
肺移植(LT)有可能延长终末期肺病患者的生存时间并提高生活质量(QOL)。本综述描述了 LT 成功的多种定义方式。它评估了随着时间的推移 LT 后生存率的提高,并描述了除移植后生存率以外衡量 LT 成功的其他方法。它还讨论了以患者为中心的结果的重要性以及健康相关生活质量(HRQL)的改善对 LT 成功定义的关键性。