Tenorio González E, Robles Díaz M, Sanjuan Jiménez R, González Grande R, Olmedo Martín R V, Rodrigo López J M, Jiménez Pérez M
UGC Aparato Digestivo, Regional University Hospital, Malaga, Spain.
UGC Aparato Digestivo y Servicio de Farmacología Clínica, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Universitario Virgen de la Victoria, Universidad de Málaga, CIBERehd, Málaga, Spain.
Transplant Proc. 2018 Mar;50(2):685-686. doi: 10.1016/j.transproceed.2017.09.059.
Hepatitis E virus (HEV) usually causes self-limiting acute liver infections from fecal or oral transmission, though other routes of infection exist (vertical transmission, blood transfusion, zoonosis). It may give rise to fulminant hepatic failure in 1% of cases. Cases have recently been reported of chronic infection evolving to cirrhosis in immunosuppressed patients, such as those with a liver or kidney transplant. Nonetheless, development of acute liver failure in these patients is exceptional, with few cases published. We present a case of acute liver failure due to HEV in a liver transplant patient who required a liver retransplant 9 years after receiving the original transplant.
戊型肝炎病毒（HEV）通常通过粪口传播引起自限性急性肝感染，不过也存在其他感染途径（垂直传播、输血、人畜共患病）。在1%的病例中，它可能导致暴发性肝衰竭。最近有报道称，免疫抑制患者（如肝或肾移植患者）会发生慢性感染并发展为肝硬化。尽管如此，这些患者发生急性肝衰竭的情况极为罕见，仅有少数病例发表。我们报告了一例肝移植患者因戊型肝炎病毒导致急性肝衰竭的病例，该患者在接受首次移植9年后需要再次进行肝移植。
