涎腺腺样囊性癌中隐匿性转移的发生率及选择性颈淋巴结清扫的状况：一项单中心研究
The incidence of occult metastasis and the status of elective neck dissection in salivary adenoid cystic carcinoma: a single center study.
作者信息
Cordesmeyer Robert, Kauffmann Philipp, Laskawi Rainer, Rau Anna, Bremmer Felix
机构信息
Department of Oral and Maxillofacial Surgery, University of Göttingen, Göttingen, Germany.
Department of Oral and Maxillofacial Surgery, University of Göttingen, Göttingen, Germany.
出版信息
Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 Jun;125(6):516-519. doi: 10.1016/j.oooo.2018.01.013. Epub 2018 Feb 2.
OBJECTIVE
Adenoid cystic carcinoma (ACC) is characterized by a high rate of local recurrence and late distant metastasis. The status of an elective neck dissection (END) is controversial in the literature.
STUDY DESIGN
In this study we retrospectively analyzed the surgical treatment and follow-up examinations of 59 patients with ACCs of a salivary gland treated in a single center between 1980 and 2016.
RESULTS
The incidence of occult nodal metastases among all patients who underwent END was 20.6%. The overall survival and the disease-free survival of patients who underwent END versus patients without END had no significant differences. Even in the case of positive lymph nodes metastasis there was no significant benefit in survival or local recurrence control.
CONCLUSION
The incidence of occult neck metastases in patients with ACC was 20.6%. There was no significant enhanced survival in the group of patients who underwent an END.
目的
腺样囊性癌（ACC）的特点是局部复发率高和远处转移晚。择区性颈清扫术（END）的地位在文献中存在争议。
研究设计
在本研究中，我们回顾性分析了1980年至2016年期间在单一中心接受治疗的59例涎腺腺样囊性癌患者的手术治疗及随访检查情况。
结果
接受END的所有患者中隐匿性淋巴结转移的发生率为20.6%。接受END的患者与未接受END的患者的总生存率和无病生存率无显著差异。即使在淋巴结转移阳性的情况下，在生存或局部复发控制方面也没有显著益处。
结论
ACC患者隐匿性颈部转移的发生率为20.6%。接受END的患者组生存率没有显著提高。
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