Suppr超能文献

男性乳腺癌的长期随访

Long Term Follow Up of Male Breast Cancer.

作者信息

McKinley N, McCain S, Kirk S

机构信息

South Eastern Health and Social Care Trust.

出版信息

Ulster Med J. 2017 Sep;86(3):177-180. Epub 2017 Sep 12.

Abstract

INTRODUCTION

Male breast cancer accounts for less than 1% of breast cancers with published overall and disease free survival being lower than in females.

AIMS

To determine treatment and long term outcomes for male breast cancer patients in our unit.

METHODS

A database has been maintained for all breast cancer patients diagnosed in our unit since 1993. Patients were identified using the database and information was collated on patient demographics, tumour pathology, treatment and outcomes using the database and retrospective chart review. Patients were followed to cause of death.

RESULTS

From 1994-2009 twenty-four cancers were diagnosed in twenty-two patients. Mean age at diagnosis was 69. Male breast cancer patients were treated using similar principles to female breast cancer. Twenty patients underwent mastectomy, two patients underwent wide local excision. No patients developed local recurrence. One patient died from their breast cancer with systemic metastases. 10-year overall survival was 22%, 10 year disease-specific survival was 80%. Other causes of death included medical co-morbidity and secondary cancers.

DISCUSSION

Disease free survival in our unit is comparable to other published studies. High age at diagnosis and co-morbidity are the most important factors in determining overall outcome. Treatment pathways for male breast cancer should follow guidelines for female disease in order to optimise outcomes. Future research at national or international level is necessary to ensure the most effective treatments are implemented for male breast cancer patients.

摘要

引言

男性乳腺癌占乳腺癌总数的比例不到1%,已发表的总体生存率和无病生存率低于女性。

目的

确定我院男性乳腺癌患者的治疗方法和长期预后。

方法

自1993年以来,我院对所有确诊的乳腺癌患者建立了数据库。通过数据库识别患者,并利用数据库和回顾性病历审查收集患者人口统计学、肿瘤病理学、治疗方法和预后等信息。对患者进行随访直至死亡原因明确。

结果

1994年至2009年期间,22名患者被诊断出患有24例癌症。确诊时的平均年龄为69岁。男性乳腺癌患者的治疗原则与女性乳腺癌相似。20例患者接受了乳房切除术,2例患者接受了局部广泛切除术。没有患者出现局部复发。1例患者因乳腺癌伴全身转移死亡。10年总生存率为22%,10年疾病特异性生存率为80%。其他死亡原因包括合并症和继发性癌症。

讨论

我院的无病生存率与其他已发表的研究相当。确诊时年龄较大和合并症是决定总体预后的最重要因素。男性乳腺癌的治疗途径应遵循女性疾病的指南,以优化治疗结果。有必要在国家或国际层面开展未来研究,以确保为男性乳腺癌患者实施最有效的治疗方法。

相似文献

1
Long Term Follow Up of Male Breast Cancer.
Ulster Med J. 2017 Sep;86(3):177-180. Epub 2017 Sep 12.
2
Male breast cancer: management and follow-up recommendations.
Breast J. 2011 Sep-Oct;17(5):503-9. doi: 10.1111/j.1524-4741.2011.01148.x. Epub 2011 Aug 29.
3
Male breast cancer: a survey at the Helsinki University Central Hospital during 1981-2006.
Acta Oncol. 2010 Apr;49(3):322-7. doi: 10.3109/02841861003591723.
5
Are males with early breast cancer treated differently from females with early breast cancer in Australia and New Zealand?
Breast. 2009 Dec;18(6):378-81. doi: 10.1016/j.breast.2009.09.015. Epub 2009 Oct 22.
6
Male breast cancer: results of the treatments and prognostic factors in 397 cases.
Eur J Cancer. 1995 Nov;31A(12):1960-4. doi: 10.1016/0959-8049(95)00366-5.
8
Male Breast Cancer: 20 Years Experience of a Tertiary Hospital from the Middle Black Sea Region of Turkey.
Asian Pac J Cancer Prev. 2015;16(15):6673-9. doi: 10.7314/apjcp.2015.16.15.6673.

引用本文的文献

1
Outcomes of Rural Men with Breast Cancer: A Multicenter Population Based Retrospective Cohort Study.
Cancers (Basel). 2023 Mar 27;15(7):1995. doi: 10.3390/cancers15071995.
3
Management and outcomes of men diagnosed with primary breast cancer.
Breast Cancer Res Treat. 2021 Jul;188(2):561-569. doi: 10.1007/s10549-021-06174-y. Epub 2021 Apr 8.
4
Metastasis pattern and prognosis of male breast cancer patients in US: a population-based study from SEER database.
Ther Adv Med Oncol. 2019 Nov 16;11:1758835919889003. doi: 10.1177/1758835919889003. eCollection 2019.
5
A rare case of primary breast angiosarcoma in a male: a case report.
BMC Cancer. 2018 Oct 16;18(1):978. doi: 10.1186/s12885-018-4895-3.

本文引用的文献

1
A Prognostic Analysis of Male Breast Cancer (MBC) Compared with Post-Menopausal Female Breast Cancer (FBC).
PLoS One. 2015 Aug 27;10(8):e0136670. doi: 10.1371/journal.pone.0136670. eCollection 2015.
2
Obesity and male breast cancer: provocative parallels?
BMC Med. 2015 Jun 4;13:134. doi: 10.1186/s12916-015-0380-x.
3
Efficacy of chemotherapy in metastatic male breast cancer patients: a retrospective study.
J Exp Clin Cancer Res. 2015 Mar 21;34(1):26. doi: 10.1186/s13046-015-0143-8.
4
Radiotherapy and Male Breast Cancer: A Population-based Registry Analysis.
Am J Clin Oncol. 2016 Oct;39(5):458-62. doi: 10.1097/COC.0000000000000078.
5
Male breast cancer according to tumor subtype and race: a population-based study.
Cancer. 2013 May 1;119(9):1611-7. doi: 10.1002/cncr.27905. Epub 2013 Jan 22.
6
Adjuvant therapy with tamoxifen compared to aromatase inhibitors for 257 male breast cancer patients.
Breast Cancer Res Treat. 2013 Jan;137(2):465-70. doi: 10.1007/s10549-012-2355-3. Epub 2012 Dec 9.
8
Male breast cancer.
Cancer Treat Rev. 2010 Oct;36(6):451-7. doi: 10.1016/j.ctrv.2010.02.002. Epub 2010 Mar 2.
9
Male breast cancer: a population-based comparison with female breast cancer.
J Clin Oncol. 2010 Jan 10;28(2):232-9. doi: 10.1200/JCO.2009.23.8162. Epub 2009 Dec 7.
10
A multicenter study of cancer incidence in CHEK2 1100delC mutation carriers.
Cancer Epidemiol Biomarkers Prev. 2006 Dec;15(12):2542-5. doi: 10.1158/1055-9965.EPI-06-0687.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验