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直肠肛管和直肠乙状结肠同步性鳞状细胞癌——病例报告

Synchronous Squamous Cell Carcinoma of the Anorectum and Proctosigmoid-a Case Report.

作者信息

Madhu Y C

机构信息

Department of Surgical Oncology, Raja Rajeswari Medical College and Hospitals, Mysore Road, Bangalore, Karnataka India.

出版信息

Indian J Surg. 2018 Feb;80(1):77-80. doi: 10.1007/s12262-017-1716-x. Epub 2017 Dec 23.

Abstract

Primary squamous cell carcinoma of the rectum is extremely rare. Squamous cell carcinoma of the anorectum is a known entity evaluation and treatment protocols have been well defined. The occurrence of squamous cell carcinoma of rectosigmoid in concurrence with squamous cell carcinoma of the anal canal is extremely rare and the first case to be reported in the literature. A 48-year-old male patient presented with difficulty in passing stools. The clinical examination, colonoscopy, and the histopathology revealed synchronous proctosigmoid and the anorectal neoplasm. A case like this will pose a diagnostic challenges; squamous cell carcinoma of the rectum is not defined in the medical literature; synchronous squamous cell carcinoma will pose both diagnostic dilemmas and treatment challenges like whether to conserve the sphincter or not. Because squamous cell carcinoma of the anorectum can be treated by chemoradiotherapy, even this case is initially thought of treating by neoadjuvant chemoradiotherapy followed by low anterior resection followed by adjuvant treatment. Since there was no medical literature to support this treatment, ultimately multidisciplinary tumor board decision was made for abdominoperineal resection. Patient was treated with abdominoperineal resection and adjuvant chemoradiation. The diagnostic dilemmas and the management issues have been discussed.

摘要

原发性直肠癌极为罕见。肛管直肠鳞状细胞癌是一种已知疾病,其评估和治疗方案已明确界定。直肠乙状结肠鳞状细胞癌与肛管鳞状细胞癌同时发生极为罕见,本文献报道的是首例。一名48岁男性患者出现排便困难。临床检查、结肠镜检查及组织病理学检查显示直肠乙状结肠和肛管直肠肿瘤同时存在。这样的病例会带来诊断挑战;医学文献中未明确直肠鳞状细胞癌;同步性鳞状细胞癌会带来诊断困境和治疗挑战,比如是否保留括约肌。由于肛管鳞状细胞癌可通过放化疗治疗,甚至最初考虑对此病例先进行新辅助放化疗,然后行低位前切除术,再进行辅助治疗。由于没有医学文献支持这种治疗方法,最终多学科肿瘤委员会决定行腹会阴联合切除术。患者接受了腹会阴联合切除术及辅助放化疗。文中讨论了诊断困境及处理问题。

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引用本文的文献

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