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2006-2015 年波兰工业区急性脑卒中的早期和 1 年预后:西里西亚脑卒中登记研究。

Early and One-Year Outcomes of Acute Stroke in the Industrial Region of Poland During the Decade 2006-2015: The Silesian Stroke Registry.

机构信息

3rd Department of Cardiology, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, Katowice, Silesian Centre for Heart Diseases, Zabrze, Poland.

Department of Basic Medical Sciences, Faculty of Public Health, Medical University of Silesia, Katowice, Poland.

出版信息

Neuroepidemiology. 2018;50(3-4):183-194. doi: 10.1159/000487324. Epub 2018 Mar 27.

Abstract

BACKGROUND

Poland, classified as a high-income country, is still considered to have a high cardiovascular risk population. During the last decade, the standards of care in acute stroke (AS) had markedly improved; thus, we aimed to assess whether and how it translated into early and late outcomes.

METHODS

Silesian Stroke Registry was created from the administrative database of the public, obligatory, health -insurer in Poland. The AS cases were selected based on primary diagnosis coded in ICD-10 as I60-I64 for years 2006-2015 (n = 120,844). Index hospitalization together with data on re-hospitalizations, procedures, ambulatory visits, rehabilitation and all-cause deaths in a 1-year follow-up were analyzed.

RESULTS

The rates of admissions per 100,000 adult population varied between 41-47 for haemorrhagic and 257-275 for ischaemic stroke with substantial decrease in almost all age groups except for the oldest patients. In ischaemic stroke, thrombolytic therapy raised from 0 to 8.8% in 2015, along with significant trends of decreasing 30-day (from 20 to 16%) and 12-month (from 35 to 31%) case fatality. In haemorrhagic stroke, case fatality had not changed. After ischaemic stroke, 12-month readmissions due to AS declined from 11-12% in 2006-2009 to 9% in 2010-2014. The percentage of patients benefiting from rehabilitation increased from 24 to 32%.

CONCLUSIONS

In a large population of industrial province, we showed recent, positive trends in AS admissions, treatment and 1-year outcomes. Development of stroke unit networks and increase in thrombolytic treatment were at least in part responsible for survival improvement and reduction of recurrence of AS. However, case-fatality and stroke recurrence remain high compared to those of other developed countries.

摘要

背景

波兰被归类为高收入国家,但仍被认为其心血管疾病高危人群比例较高。在过去十年中,急性脑卒中(AS)的治疗标准有了显著改善;因此,我们旨在评估这种改善是否以及如何转化为早期和晚期结果。

方法

从波兰公共、强制性、医疗保险机构的行政数据库中创建了西里西亚卒中登记处。根据 2006-2015 年 ICD-10 中编码为 I60-I64 的主要诊断选择 AS 病例(n=120844)。分析索引住院以及 1 年随访期间的再住院、程序、门诊就诊、康复和全因死亡的数据。

结果

成人每 10 万人的入院率在脑出血为 41-47 例,缺血性卒为 257-275 例之间变化,除了最年长的患者外,几乎所有年龄段的入院率都在下降。在缺血性卒中中,溶栓治疗从 2015 年的 0 上升到 8.8%,同时 30 天(从 20%下降到 16%)和 12 个月(从 35%下降到 31%)的病死率呈显著下降趋势。在脑出血中,病死率没有变化。在缺血性卒中后,由于 AS 的 12 个月再入院率从 2006-2009 年的 11-12%下降到 2010-2014 年的 9%。受益于康复治疗的患者比例从 24%上升到 32%。

结论

在一个工业省份的大人群中,我们显示了最近 AS 入院、治疗和 1 年结果的积极趋势。卒中单元网络的发展和溶栓治疗的增加至少部分解释了生存率的提高和 AS 复发的减少。然而,与其他发达国家相比,病死率和卒中复发率仍然很高。

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