College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Korea.
College of Pharmacy, Yeungnam University, Gyeongsan 38541, Korea.
Molecules. 2018 Mar 24;23(4):752. doi: 10.3390/molecules23040752.
Two new ω-phenylpentaene fatty acid amide diglycosides, rhamnellosides A () and B (), were isolated from the fruits of (Rhamnaceae). These compounds were prioritized using LC-MS/MS molecular networking dereplication based on our previous discovery of 2-acetoxy-ω-phenylpentaene fatty acid triglycosides berchemiosides A-C from a phylogenetically related species, . The structures of the isolated compounds were elucidated by spectroscopic analyses in combination with chemical derivatization. The pentaene groups of and were found to have (6, 8, 10, 12, 14)-geometry, which is the same as that found in berchemioside A.
从 （Rhamnaceae）的果实中分离得到两种新的 ω-苯基戊烯脂肪酸酰胺二糖苷，鼠李糖苷 A () 和 B ()。这些化合物是根据我们之前从系统发育上相关的物种 （）中发现的 2-乙酰氧基-ω-苯基戊烯脂肪酸三糖苷 berchemiosides A-C，使用 LC-MS/MS 分子网络去重复化技术优先确定的。通过光谱分析结合化学衍生化，阐明了分离化合物的结构。和 的戊烯基团均具有 (6, 8, 10, 12, 14)-构型，与 berchemioside A 中的相同。
