Shen Yu-xia, Teng Hong-li, Yang Guang-zhong, Mei Zhi-nan, Chen Xiao-long
College of Pharmacy, South-Central University for Nationalities, Wuhan 430074, China.
Yao Xue Xue Bao. 2010 Sep;45(9):1139-43.
To study the chemical constituents from the root of Berchemia lineata (L.) DC., nine compounds were isolated from the EtOAc extract by using silica gel, RP-C18 silica gel column chromatography and preparative HPLC. Based on the spectroscopic analysis, their structures were identified as 5-hydroxy-7-(2'-hydroxypropyl)-2-methyl-chromone (1), (-)-(1'R, 2'S)-erythro-5-hydroxy-7-(1', 2'-dihydroxypropyl)-2-methyl-chromone (2), naringenin (3), eriodictyol (4), (+)-aromadendrin (5), (+)-taxifolin (6), (+)-catechin (7), (+)-epigallocatechin (8) and quercetin (9). Among them, compound 2 is a new chromone derivative. Compound 1 is a known chromone derivative and isolated from this genus for the first time. Compounds 3-9 are known flavonoids and isolated from this plant for the first time.
为研究毛背勾儿茶(Berchemia lineata (L.) DC.)根中的化学成分,采用硅胶、RP-C18硅胶柱色谱和制备型高效液相色谱法从其乙酸乙酯提取物中分离得到9个化合物。通过光谱分析,确定它们的结构分别为5-羟基-7-(2'-羟丙基)-2-甲基色酮(1)、(-)-(1'R, 2'S)-赤式-5-羟基-7-(1', 2'-二羟基丙基)-2-甲基色酮(2)、柚皮素(3)、圣草酚(4)、(+)-二氢山奈酚(5)、(+)-花旗松素(6)、(+)-儿茶素(7)、(+)-表没食子儿茶素(8)和槲皮素(9)。其中,化合物2是一种新的色酮衍生物。化合物1是一种已知的色酮衍生物,首次从该属植物中分离得到。化合物3-9是已知的黄酮类化合物,首次从该植物中分离得到。