School of Public Health, Curtin University, Perth, WA 6845, Australia.
Australian Research Centre for Population Oral Health, The University of Adelaide, Adelaide, SA 5000, Australia.
Int J Environ Res Public Health. 2018 Mar 26;15(4):599. doi: 10.3390/ijerph15040599.
This study aimed to determine whether breastfeeding duration and the timing of solid food were independently associated with being overweight or obese in early childhood. Subjects were 953 children participating in the Study of Mothers and Infants Life Events Affecting Oral Health (SMILE) birth cohort study, based in Adelaide, Australia. Socio-demographic information and data on breastfeeding duration and age of introduction of solid food were collected at birth, 3, 4, 6, 12, and 24 months via mailed or online questionnaires completed by mothers. The weight and height of children were measured at a dental examination when children were aged between 24 and 36 months. Body mass index was calculated, and children were categorised into weight groups according to the World Health Organization growth standards. Multivariable logistic regression analysis was conducted, adjusting for maternal age at birth, education, socio-economic status, pre-pregnancy weight, smoking in pregnancy, method of delivery, and child's birthweight. Risk of overweight/obesity was independently associated with maternal pre-pregnancy BMI, smoking in pregnancy, and birthweight. Children that were breastfed for 12 months or more had a significantly lower risk of being overweight/obese than those breastfed for less than 17 weeks (AOR 0.49; 95%CI 0.27, 0.90; for trend =0.009). Age of introduction of solid food, however, was not associated with the risk of being overweight/obese at 24 to 36 months. This study provides further evidence of an inverse relationship between breastfeeding and risk of overweight/obesity, however, no association with the timing of solid food was detected.
本研究旨在确定母乳喂养持续时间和固体食物引入时间是否与儿童早期超重或肥胖独立相关。研究对象为 953 名参与澳大利亚阿德莱德的母婴生活事件影响口腔健康研究(SMILE)出生队列研究的儿童。在出生时、3 个月、4 个月、6 个月、12 个月和 24 个月,通过邮寄或在线问卷收集了母亲的社会人口统计学信息以及母乳喂养持续时间和固体食物引入年龄的数据。当儿童年龄在 24 至 36 个月之间时,通过牙科检查测量儿童的体重和身高。计算体重指数,并根据世界卫生组织的生长标准将儿童分为体重组。进行多变量逻辑回归分析,调整母亲的出生年龄、教育程度、社会经济地位、孕前体重、孕期吸烟、分娩方式和儿童出生体重。超重/肥胖的风险与母亲的孕前 BMI、孕期吸烟和出生体重独立相关。母乳喂养 12 个月或以上的儿童超重/肥胖的风险显著低于母乳喂养不足 17 周的儿童(OR 0.49;95%CI 0.27,0.90;趋势=0.009)。然而,固体食物引入的年龄与 24 至 36 个月时超重/肥胖的风险无关。本研究进一步证明了母乳喂养与超重/肥胖风险之间的反比关系,但未发现与固体食物引入时间的关联。