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[用于糖尿病门诊治疗的胰岛素输注泵]

[Pumps for insulin infusion in the ambulatory treatment of diabetes mellitus].

作者信息

Mirouze J

机构信息

Clinique des Maladies métaboliques et endocriennes, Hôpital Lapeyronie, Montpellier.

出版信息

Presse Med. 1987 Oct 3;16(32):1585-90.

PMID:2958834
Abstract

Insulin infusions given by portable pumps constitute a recent therapeutic advance in those difficult cases of diabetes mellitus which cannot be stabilized by repeated conventional injections. The different varieties of pumps, catheters and insulins used are described. The intravenous and intraperitoneal routes of administration have given results superior to those of the subcutaneous route. Short-term results are evaluated by change in blood glucose levels, medium-term results by glycosylated haemoglobin levels and various metabolic and hormonal abnormalities, and long-term results mostly by the influence of treatment on degenerative complications of diabetes. The metabolic and infectious incidents and accidents of the method as well as its psychological advantages and drawbacks are discussed.

摘要

便携式泵输注胰岛素是糖尿病治疗的一项新进展,适用于那些经反复常规注射仍无法稳定病情的复杂病例。文中描述了所使用的不同类型的泵、导管和胰岛素。静脉和腹腔给药途径的效果优于皮下给药途径。短期效果通过血糖水平的变化来评估,中期效果通过糖化血红蛋白水平以及各种代谢和激素异常情况来评估,长期效果主要通过治疗对糖尿病退行性并发症的影响来评估。文中还讨论了该方法的代谢和感染事件及意外情况,以及其心理方面的优缺点。

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