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本文引用的文献

1

Extent, location, and clinical significance of non-infarct-related coronary artery disease among patients with ST-elevation myocardial infarction.ST 段抬高型心肌梗死患者中非梗死相关冠状动脉疾病的范围、部位和临床意义。

JAMA. 2014 Nov 19;312(19):2019-27. doi: 10.1001/jama.2014.15095.

2

Culprit vessel versus multivessel intervention at the time of primary percutaneous coronary intervention in patients with ST-segment-elevation myocardial infarction and multivessel disease: real-world analysis of 3984 patients in London.ST段抬高型心肌梗死合并多支血管病变患者在直接经皮冠状动脉介入治疗时罪犯血管与多支血管干预：伦敦3984例患者的真实世界分析

Circ Cardiovasc Qual Outcomes. 2014 Nov;7(6):936-43. doi: 10.1161/CIRCOUTCOMES.114.001194. Epub 2014 Nov 4.

3

2014 ESC/EACTS Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)Developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI).2014年欧洲心脏病学会/欧洲心胸外科学会心肌血运重建指南：欧洲心脏病学会（ESC）和欧洲心胸外科学会（EACTS）心肌血运重建特别工作组编写，欧洲经皮心血管介入协会（EAPCI）提供特别贡献。

Eur Heart J. 2014 Oct 1;35(37):2541-619. doi: 10.1093/eurheartj/ehu278. Epub 2014 Aug 29.

4

Randomized trial of preventive angioplasty in myocardial infarction.随机对照试验预防心肌梗死的血管成形术。

N Engl J Med. 2013 Sep 19;369(12):1115-23. doi: 10.1056/NEJMoa1305520. Epub 2013 Sep 1.

5

2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.2013年美国心脏病学会基金会/美国心脏协会ST段抬高型心肌梗死管理指南：执行摘要：美国心脏病学会基金会/美国心脏协会实践指南工作组报告

Circulation. 2013 Jan 29;127(4):529-55. doi: 10.1161/CIR.0b013e3182742c84. Epub 2012 Dec 17.

6

ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation.ST段抬高型急性心肌梗死患者管理的欧洲心脏病学会指南

Eur Heart J. 2012 Oct;33(20):2569-619. doi: 10.1093/eurheartj/ehs215. Epub 2012 Aug 24.

7

Impact of multivessel coronary artery disease and noninfarct-related artery revascularization on outcome of patients with ST-elevation myocardial infarction transferred for primary percutaneous coronary intervention (from the EUROTRANSFER Registry).多支冠状动脉疾病及非梗死相关动脉血运重建对接受直接经皮冠状动脉介入治疗的ST段抬高型心肌梗死患者预后的影响（来自欧洲转运注册研究）

Am J Cardiol. 2010 Aug 1;106(3):342-7. doi: 10.1016/j.amjcard.2010.03.029. Epub 2010 Jun 18.

8

Non-culprit coronary artery percutaneous coronary intervention during acute ST-segment elevation myocardial infarction: insights from the APEX-AMI trial.急性 ST 段抬高型心肌梗死时非罪犯血管经皮冠状动脉介入治疗：来自 APEX-AMI 试验的观察。

Eur Heart J. 2010 Jul;31(14):1701-7. doi: 10.1093/eurheartj/ehq129. Epub 2010 Jun 8.

9

Culprit vessel percutaneous coronary intervention versus multivessel and staged percutaneous coronary intervention for ST-segment elevation myocardial infarction patients with multivessel disease.罪犯血管经皮冠状动脉介入治疗与多血管和分期经皮冠状动脉介入治疗 ST 段抬高型心肌梗死合并多血管病变患者。

JACC Cardiovasc Interv. 2010 Jan;3(1):22-31. doi: 10.1016/j.jcin.2009.10.017.

10

A randomised trial of target-vessel versus multi-vessel revascularisation in ST-elevation myocardial infarction: major adverse cardiac events during long-term follow-up.随机化研究显示 ST 段抬高型心肌梗死患者罪犯血管与多支血管血运重建的比较：长期随访期间主要不良心脏事件。

Heart. 2010 May;96(9):662-7. doi: 10.1136/hrt.2009.177162. Epub 2009 Sep 23.

ST段抬高型心肌梗死的预防性经皮冠状动脉介入治疗——随机试验的首要地位

Preventive Percutaneous Coronary Intervention in ST-elevation Myocardial Infarction - The Primacy of Randomised Trials.

作者信息

Wald David S, Bestwick Jonathan P

机构信息

Professor of Cardiology.

Lecturer in Medical Statistics, Wolfson Institute of Preventive Medicine, London, UK.

出版信息

Interv Cardiol. 2015 Mar;10(1):32-34. doi: 10.15420/icr.2015.10.1.32.

DOI:10.15420/icr.2015.10.1.32

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5808670/

Abstract

Randomised trials show a benefit of preventive (non-infarct artery) percutaneous coronary intervention in patients with acute ST elevation myocardial infarction, but non-randomised studies do not. The evidence on each is quantified and assessed. The primacy of randomised trials reveals the danger of using non-randomised studies that can, as in this case, give the wrong answer.

摘要

随机试验表明，对于急性ST段抬高型心肌梗死患者，预防性（非梗死相关动脉）经皮冠状动脉介入治疗有益，但非随机研究则未显示出此益处。对二者的证据进行了量化和评估。随机试验的首要地位揭示了使用非随机研究的风险，就像在这个案例中，非随机研究可能会给出错误答案。