Kliger Chad
Division of Structural and Congenital Heart Disease, Lenox Hill Heart and Vascular Institute - North Shore/LIJ Health System, New York, US.
Interv Cardiol. 2014 Mar;9(1):49-53. doi: 10.15420/icr.2011.9.1.49.
Mitral regurgitation is a complex disorder involving a multitude of components of the mitral apparatus. With the desire for less invasive treatment approaches, transcatheter mitral valve therapies (TMVT) are directed at these components and available at varying stages of development. Therapeutic advancements and the potential to combine technologies may further improve their efficacy and safety. Transcatheter mitral valve replacement, while preserving the mitral apparatus, may emerge as an alternative or even a more suitable treatment option. In addition, early data on transcatheter mitral valve-in-valve and valve-in-ring implantation are encouraging and this approach may be an alternative to reoperation in the high-risk patient. This review details the expanding functional mechanical designs of current active TMVT.
二尖瓣反流是一种复杂的疾病,涉及二尖瓣装置的多个组成部分。随着对侵入性较小的治疗方法的需求,经导管二尖瓣治疗(TMVT)针对这些组成部分,并且处于不同的发展阶段。治疗进展以及技术联合应用的潜力可能会进一步提高其疗效和安全性。经导管二尖瓣置换术在保留二尖瓣装置的同时,可能会成为一种替代方案,甚至是更合适的治疗选择。此外,经导管二尖瓣瓣中瓣和瓣中环植入的早期数据令人鼓舞,这种方法可能是高危患者再次手术的替代方案。本综述详细介绍了当前有源TMVT不断扩展的功能性机械设计。