Marechal Patrick, Davin Laurent, Gach Olivier, Martinez Christophe, Lempereur Mathieu, Lhoest Nicolas, Lancellotti Patrizio
a GIGA Cardiovascular Sciences, Departments of Cardiology, Heart Valve Clinic, CHU Sart Tilman , University of Liège Hospital , Liège , Belgium.
b Clinique de l'Orangerie , GERC , Strasbourg , France.
Expert Rev Cardiovasc Ther. 2018 May;16(5):361-367. doi: 10.1080/14779072.2018.1459187. Epub 2018 Apr 2.
Despite an incidence of about 18-52% of the patients undergoing coronary angiography, chronic total occlusions (CTO) are rarely revascularised by percutaneous angioplasty (PCI). Nevertheless, current evidence suggests that successful CTO angioplasty improves symptoms, quality of life and long-term survival. During the last decade, the improvement of specific tools and techniques for these complex procedures, and the increasing experience of operators, have led to the achievement of success and complication rates almost equivalent to non-CTO angioplasty. Areas covered: This review focuses on the clinical benefits of CTO revascularization and on appropriate patient selection. Expert commentary: Current evidence suggests that successful CTO-PCI improves symptoms, quality of life and long-term survival. During the last years, the improvement of specific techniques for these complex procedures and the increasing experience of operators, have led to the achievement of success and complication rates almost equivalent to non-CTO lesion angioplasty.
尽管接受冠状动脉造影的患者中慢性完全闭塞（CTO）的发生率约为18% - 52%，但经皮血管成形术（PCI）很少能使慢性完全闭塞病变实现血运重建。然而，目前的证据表明，成功的CTO血管成形术可改善症状、提高生活质量并延长长期生存率。在过去十年中，针对这些复杂手术的特定工具和技术的改进以及术者经验的增加，已使成功率和并发症发生率达到几乎与非CTO血管成形术相当的水平。涵盖领域：本综述重点关注CTO血运重建的临床益处以及合适的患者选择。专家评论：目前的证据表明，成功的CTO - PCI可改善症状、提高生活质量并延长长期生存率。在过去几年中，针对这些复杂手术的特定技术的改进以及术者经验的增加，已使成功率和并发症发生率达到几乎与非CTO病变血管成形术相当的水平。
