高价金属阳离子和环状多胺对噬菌体φX174感染性的抑制作用。
The inhibition of infectivity of bacteriophage phi X174 by high-valency metal cations and cyclic polyamines.
作者信息
Rowatt E, Williams R J
机构信息
Department of Microbiology, School of Pathology, Middlesex Hospital Medical School, London, U.K.
出版信息
Biochem J. 1987 Aug 1;245(3):641-7. doi: 10.1042/bj2450641.
It has been shown previously that many aliphatic polyamines and metal cations decrease the infectivity of bacteriophage phi X174 when lipopolysaccharide from Escherichia coli C is present. Cations of higher charge are more effective. In the present paper it is shown that certain of the metal cations and cyclic polyamines diminish phage infectivity without lipopolysaccharide. The relation of cation concentration to loss of infectivity is different for the two types of reaction. In the absence of lipopolysaccharide the inhibition increases with the charge of the cation, but that by cyclic polyamines depends also on the hydrocarbon chains and their conformation. Some characteristics of the reactions are discussed.
先前已表明，当存在来自大肠杆菌C的脂多糖时，许多脂肪族多胺和金属阳离子会降低噬菌体φX174的感染性。电荷较高的阳离子更有效。在本文中表明，某些金属阳离子和环状多胺在没有脂多糖的情况下也会降低噬菌体感染性。两种反应中阳离子浓度与感染性丧失的关系不同。在没有脂多糖的情况下，抑制作用随阳离子电荷增加而增强，但环状多胺引起的抑制作用还取决于烃链及其构象。本文讨论了这些反应的一些特性。
Zotero 插件