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多价离子对大肠杆菌C来源的脂多糖使噬菌体φX174失活的影响。

The effect of multivalent ions on the inactivation of bacteriophage phi X174 by lipopolysaccharide from Escherichia coli C.

作者信息

Rowatt E, Williams R J

出版信息

Biochem J. 1985 Nov 1;231(3):765-8. doi: 10.1042/bj2310765.

Abstract

The inactivation of bacteriophage phi X174 by lipopolysaccharide from Escherichia coli C is promoted by multivalent metal ions and by polyamines. The effect of the two types of cation is similar, and the concentration causing 50% inactivation varies inversely with the charge on the cation, although quadrivalent amines are less active than expected. The increase in activity as the charge rises suggests that electrostatic binding is overwhelmingly important.

摘要

来自大肠杆菌C的脂多糖对噬菌体φX174的灭活作用可被多价金属离子和多胺促进。这两类阳离子的作用相似,引起50%灭活的浓度与阳离子的电荷呈反比,尽管四价胺的活性低于预期。随着电荷增加活性增强,这表明静电结合极为重要。

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