Pitts-Tucker Toby, Small Jeremy
Department of Geriatric Medicine, Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust, Bournemouth, UK.
Department of Radiology, Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust, Bournemouth, UK.
BMJ Case Rep. 2018 Mar 28;2018:bcr-2017-222185. doi: 10.1136/bcr-2017-222185.
An 86-year-old woman was admitted with multiple episodes of transient loss of consciousness. She was initially treated for seizures, and stroke was not considered likely. MRI on the same day of admission showed acute bilateral medial thalamic infarcts in keeping with the Artery of Percheron (AOP) territory infarcts. Investigation for polycythaemia and thrombocytosis showed JAK2 positive myeloproliferative neoplasm.A diagnosis of AOP infarction is often missed or delayed because it is rare and presents with variable neurological symptoms. Initial imaging in the form of CT is often negative, and some report that initial MRI findings may also be normal.An awareness of a wide range of differential diagnoses alongside a multi-modality imaging approach is required to reach a diagnosis.Although there are several other case reports of AOP infarction in the literature, this is the first to present with transient symptoms initially mistaken for seizure activity.
一名86岁女性因多次短暂性意识丧失入院。她最初接受了癫痫治疗,当时认为不太可能是中风。入院当天的MRI显示双侧丘脑内侧急性梗死,符合Percheron动脉(AOP)区域梗死。对红细胞增多症和血小板增多症的检查显示JAK2阳性骨髓增殖性肿瘤。由于AOP梗死罕见且表现出多样的神经症状,其诊断常常被漏诊或延误。CT形式的初始影像学检查通常为阴性,一些报告称初始MRI检查结果也可能正常。需要具备广泛的鉴别诊断意识以及多模态影像学检查方法才能做出诊断。尽管文献中有其他几例AOP梗死的病例报告,但这是首例最初表现为短暂症状且被误诊为癫痫活动的病例。