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莫达非尼成瘾:一例合并注意缺陷多动障碍的病例

Modafinil Dependence: A Case with Attention-Deficit/Hyperactivity Disorder.

作者信息

Alacam Huseyin, Basay Omer, Tumkaya Selim, Mart Mehmet, Kar Gokce

机构信息

Department of Psychiatry, Faculty of Medicine, Pamukkale University, Denizli, Turkey.

Department of Child and Adolescent Psychiatry, Faculty of Medicine, Pamukkale University, Denizli, Turkey.

出版信息

Psychiatry Investig. 2018 Apr;15(4):424-427. doi: 10.30773/pi.2016.10.25. Epub 2018 Mar 30.

Abstract

Modafinil is generally known as a drug with low addiction potential. There are few case reports in the literature demonstrating that Modafinil, stated being capable of diminishing symptoms of attention deficit/hyperactivity disorder (ADHD), causes addiction. In the present article a Modafinil addicted ADHD case, consuming usurious doses (5,000 mg/per day) of Modafinil is presented. The case presented to our psychiatry outpatient clinic due to: requirement of in taking high dose Modafinil in order to achieve the initial effects, difficulty in obtaining the drug, irritability, anxiousness, sleep irregularities, fatigue and unpleasant vivid dreams when he did not use the drug. It was realized that the patient, himself increased doses of Modafinil incrementally, in order to keep its effects on attention symptoms at the same level. It has to be kept in mind that ADHD patients can develop Modafinil addiction. It is necessary to carry out systemic studies on this subject.

摘要

莫达非尼通常被认为是一种成瘾潜力较低的药物。文献中很少有病例报告表明,据称能够减轻注意力缺陷多动障碍(ADHD)症状的莫达非尼会导致成瘾。在本文中,介绍了一例对莫达非尼成瘾的ADHD病例,该患者服用了超高剂量(每天5000毫克)的莫达非尼。该病例因以下原因前来我们的精神科门诊:为了达到初始效果需要服用高剂量莫达非尼、获取药物困难、易怒、焦虑、睡眠不规律、疲劳以及不服用药物时出现不愉快的生动梦境。经了解,患者为了使药物对注意力症状的效果保持在同一水平,自行逐渐增加莫达非尼的剂量。必须牢记,ADHD患者可能会对莫达非尼产生成瘾。有必要针对这一主题开展系统性研究。

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