Chai W G, Yan L, Wang G H, Liang X Y, Zhao Y F, Ji G J
Institute of Chemistry, Chinese Academy of Sciences, Beijing.
Biomed Environ Mass Spectrom. 1987 Jul;14(7):331-3. doi: 10.1002/bms.1200140706.
Positive ion fast atom bombardment mass spectrometric sensitivities of seven amino acids and the corresponding di-isopropylphosphorylated derivatives were carefully compared. Results showed that an improvement in sensitivity by factors of 4-29, mostly above 10, were achieved after the derivatization. The chemical noise derived from glycerol matrix was also greatly reduced by this derivatization.
