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13 岁男孩舞蹈症表现的系统性红斑狼疮:病例报告及文献复习。

Chorea revealing systemic lupus erythematosus in a 13-year old boy: A case report and short review of the literature.

机构信息

a Department of Paediatrics , Venizeleion General Hospital , Heraklion, Crete , Greece.

b Peadiatric Neurology Clinics, Venizeleion General Hospital , Heraklion, Crete , Greece.

出版信息

Int Rev Immunol. 2018;37(4):177-182. doi: 10.1080/08830185.2018.1452920. Epub 2018 Mar 29.

DOI:10.1080/08830185.2018.1452920
PMID:29595356
Abstract

Among the neurological manifestations of systemic lupus erythematosus (SLE), chorea is rare, presenting in less than 7% of the pediatric SLE patients. It can appear early in the onset of SLE, be the first or even the sole clinical feature of the illness and has strongly been associated with the presence of antiphospholipid antibodies. We report on the case of a 13-year old boy, admitted with acute onset chorea and finally diagnosed with SLE. Subsequently, we present a short review of the literature on the epidemiology, suggested pathogenesis, clinical presentation and treatment of this rare presentation of SLE.

摘要

在系统性红斑狼疮(SLE)的神经表现中,舞蹈病较为罕见,在儿科 SLE 患者中不到 7%。它可以在 SLE 发病早期出现,是疾病的首发甚至唯一临床特征,且与抗磷脂抗体的存在密切相关。我们报告了一例 13 岁男孩,以急性起病的舞蹈病入院,最终诊断为 SLE。随后,我们对 SLE 这种罕见表现的流行病学、推测发病机制、临床表现和治疗进行了文献复习。

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