Division of Ophthalmology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
Department of Ophthalmology, First Hospital of China Medical University, Shenyang, People's Republic of China.
Retina. 2019 Jun;39(6):1054-1060. doi: 10.1097/IAE.0000000000002116.
To evaluate the capacity of spectral domain optical coherence tomography macular findings to predict best-corrected visual acuity (BCVA) outcomes after treatment for symptomatic vitreomacular traction.
This consecutive, retrospective study included 24 patients (29 eyes) who experienced vitreomacular traction release with pneumatic vitreolysis (n = 9), intravitreal ocriplasmin (n = 6), or pars plana vitrectomy (n = 14). Preoperative and postoperative spectral domain optical coherence tomography images were used to determine the cone outer segment tips (COST) line, inner segment/outer segment line, and other frequently used features. Correlations between optical coherence tomography findings and BCVA were determined using regression analyses.
Postoperative BCVA was correlated with length of the COST line and inner segment/outer segment line defects at 1, 3, 6, and 12 months postoperatively (P < 0.05) by simple linear regression analysis. However, multivariable regression analysis showed that only length of the COST line defect was significantly correlated with BCVA preoperatively and postoperatively (P < 0.05). Postoperative BCVA improvement at 12 months was significantly correlated with preoperative length of the COST line defect (P < 0.01).
Recovery of the COST line and inner segment/outer segment line defects as observed by spectral domain optical coherence tomography is positively correlated with visual acuity improvement after successful vitreomacular traction treatment. Best-corrected visual acuity improvement may be predicted using the length of the preoperative COST line defect.
评估频域光相干断层扫描（OCT）黄斑区检查结果预测治疗症状性玻璃体黄斑牵引后最佳矫正视力（BCVA）的能力。
这是一项连续的回顾性研究，共纳入 24 名（29 只眼）接受玻璃体黄斑牵引松解术的患者，其中行气动玻璃体切割术（n=9）、玻璃体内注射 ocriplasmin（n=6）或标准玻璃体切除术（n=14）。使用术前和术后频域 OCT 图像确定锥体外节尖端（COST）线、内节/外节线和其他常用特征。使用回归分析确定 OCT 检查结果与 BCVA 之间的相关性。
简单线性回归分析显示，术后 BCVA 与术后 1、3、6 和 12 个月的 COST 线和内节/外节线缺损长度相关（P<0.05）。然而，多变量回归分析显示，仅 COST 线缺损长度与术前和术后 BCVA 显著相关（P<0.05）。术后 12 个月 BCVA 的改善与术前 COST 线缺损长度显著相关（P<0.01）。
频域 OCT 观察到的 COST 线和内节/外节线缺损的恢复与玻璃体黄斑牵引治疗成功后的视力提高呈正相关。可以使用术前 COST 线缺损长度预测最佳矫正视力的改善。
