1 Palliative Medical Unit, Grantham Hospital , Aberdeen, Hong Kong .
2 Division of Nephrology, Department of Medicine, Queen Mary Hospital, University of Hong Kong , Pok Fu Lam, Hong Kong .
J Palliat Med. 2018 Jun;21(6):809-814. doi: 10.1089/jpm.2017.0505. Epub 2018 Mar 12.
There is little data on pain management in patients with advanced chronic kidney disease (CKD) who have opted for palliative care.
We investigated the prevalence, severity and management of pain in advanced CKD patients attending Renal Palliative Care out-patient clinics under our Division.
Consecutive patients referred to the Renal Palliative Care Clinics at two hospitals under our Division from July 2012 to June 2016 were included. All the patients were managed according to a multi-disciplinary protocol led by palliative care specialists, including serial assessments with the Edmonton Symptom Assessment System.
Response to pain management was defined as a difference by 2 points or more, and factors predictive of response were assessed by logistic regression.
Data from 253 patients were analyzed. Of them 107 patients (42%) experienced pain symptoms: 45 patients (42.1%) rated their pain as mild (score 0-3), 51 (47.7%) as moderate (NRS score 4-6), and 11 (10.2%) as severe (score 7-10) by using numerical rating scale. The response rate to pain management was 53.2%. Neuropathic pain was a predictor for lack of response.
Pain is common in advanced CKD patients receiving palliative care. While this seems to have been underrecognized, the symptom is potentially amenable to management. We recommend routine assessment of pain burden in this patient population.
选择姑息治疗的晚期慢性肾脏病(CKD)患者的疼痛管理数据很少。
我们研究了我们科室姑息治疗门诊就诊的晚期 CKD 患者疼痛的发生率、严重程度和管理情况。
纳入 2012 年 7 月至 2016 年 6 月期间,我们科室的两家医院的姑息治疗门诊连续就诊的患者。所有患者均根据姑息治疗专家领导的多学科方案进行管理,包括使用埃德蒙顿症状评估系统进行定期评估。
疼痛管理的反应定义为相差 2 分或更多,并用逻辑回归评估反应的预测因素。
分析了 253 例患者的数据。其中 107 例(42%)患者出现疼痛症状:45 例(42.1%)患者疼痛程度为轻度(评分 0-3),51 例(47.7%)为中度(NRS 评分 4-6),11 例(10.2%)为重度(评分 7-10)。疼痛管理的反应率为 53.2%。神经病理性疼痛是反应不佳的预测因素。
疼痛是接受姑息治疗的晚期 CKD 患者的常见症状。虽然这似乎被低估了,但这种症状是可以治疗的。我们建议对这一患者群体的疼痛负担进行常规评估。