Tyrer P, Alexander J, Remington M, Riley P
Mapperley Hospital, Nottingham, U.K.
J Affect Disord. 1987 Jul-Aug;13(1):13-21. doi: 10.1016/0165-0327(87)90069-3.
Symptoms of anxiety, panic, depression, hypochondriasis and phobias were recorded serially over a 2-year period in 78 psychiatric patients with depressive, anxiety and phobic neuroses. It was hypothesised that if there was a clear-cut relationship between symptom type and diagnosis the current classification of neurotic disorder would be supported. The results showed great temporal variability of anxiety and depressive symptoms. These symptoms were also poorly related to diagnosis. Phobic symptoms, however, were relatively consistent over time. The findings suggest that classifications of neurotic disorder based on presenting anxiety and depressive symptoms are unsatisfactory and that many patients could be classified as a single mixed disorder.
在78例患有抑郁、焦虑和恐怖性神经症的精神科患者中,对其焦虑、惊恐、抑郁、疑病症和恐惧症症状进行了为期2年的连续记录。研究假设,如果症状类型与诊断之间存在明确关系,那么当前的神经症性障碍分类将得到支持。结果显示,焦虑和抑郁症状在时间上有很大的变异性。这些症状与诊断的相关性也很差。然而,恐怖症状随时间相对较为一致。研究结果表明,基于所呈现的焦虑和抑郁症状对神经症性障碍进行分类并不令人满意,而且许多患者可能被归类为单一的混合性障碍。