Zuckerman A J
Department of Medical Microbiology, London School of Hygiene and Tropical Medicine, UK.
Postgrad Med J. 1986;62 Suppl 2:3-10.
The high rate of infection with hepatitis B virus in certain defined populations in industralized countries and among the general population in many non-industrialized countries stresses the need for hepatitis B vaccines. Hepatitis B, one of at least six different forms of viral hepatitis, may progress to chronic liver disease, including chronic persistent hepatitis, chronic active hepatitis, cirrhosis and primary liver cancer. Primary liver cancer is one of the ten most common cancers in the world today. Immunization against hepatitis B is required therefore for groups at high risk of infection according to epidemiological patterns, socioeconomic factors, cultural and sexual practices and the environment.
在工业化国家某些特定人群以及许多非工业化国家的普通人群中，乙肝病毒的高感染率凸显了乙肝疫苗的必要性。乙肝是至少六种不同形式的病毒性肝炎之一，可能会发展为慢性肝病，包括慢性持续性肝炎、慢性活动性肝炎、肝硬化和原发性肝癌。原发性肝癌是当今世界十大最常见癌症之一。因此，根据流行病学模式、社会经济因素、文化和性行为以及环境，针对高感染风险人群需要接种乙肝疫苗。
