Sachs R N, Larmignat P, Azorin J, Tellier P, Fischbein L, Cadilhac P, Cupa M, de Saint Florent G, Vulpillat M, Lanfranchi J
Service de Médicine interne et Cardiologie, Hôpital Avicenne, Bobigny.
Presse Med. 1987 Oct 17;16(34):1685-8.
From October 1983 to January 1985, 46 patients (38 men and 8 women; mean age 60 years, range 37-83) underwent peripheral vascular surgery either of the internal carotid artery or of arteries of the lower limbs. All patients had thorough clinical examination, ECG and thallium dipyridamole myocardial scanning before operation, as a result of which they were divided into 20 with, and 26 without chronic ischemic heart disease. Three major cardiac events were noted during or following a period of one month after surgery: two deaths due to a cardiac ischemic event and one post-operative unstable angina pectoris. The three patients with these complications were classified in the coronary group (NS). When the patients were reclassified according to the presence or absence of thallium redistribution on serial images after dipyridamole, 14 had redistribution and 32 had no redistribution. The three major cardiac events were found to have occurred in the group with redistribution (P less than 0.04). Our study suggests that patients with redistribution have a high incidence of postoperative ischemic events. They should be considered for a particular pre-operative coronary management to avoid post-operative major cardiac events and to improve survival.
1983年10月至1985年1月,46例患者(38例男性,8例女性;平均年龄60岁,范围37 - 83岁)接受了颈内动脉或下肢动脉的外周血管手术。所有患者在手术前均接受了全面的临床检查、心电图检查和双嘧达莫铊心肌扫描,据此将他们分为20例患有慢性缺血性心脏病和26例未患慢性缺血性心脏病的患者。在术后1个月内或术后观察期间,记录到3例主要心脏事件:2例因心脏缺血事件死亡,1例术后不稳定型心绞痛。这3例出现并发症的患者被归类于冠心病组(无统计学意义)。当根据双嘧达莫后系列图像上铊再分布情况对患者重新分类时,14例有再分布,32例无再分布。发现3例主要心脏事件均发生在有再分布的组中(P小于0.04)。我们的研究表明,有再分布的患者术后缺血事件发生率较高。应考虑对他们进行特殊的术前冠状动脉管理,以避免术后主要心脏事件并提高生存率。