Sachs R N, Tellier P, Larmignat P, Azorin J, Fischbein L, Beaudet B, Cadilhac P, Cupa M, De Saint Florent G, Vulpillat M
Service of Internal Medicine, Hôpital Avicenne, Bobigny, France.
Surgery. 1988 May;103(5):584-7.
From October 1983 to January 1985, 46 patients (38 men and 8 women; average age, 60 years; range, 37 to 83 years) underwent peripheral vascular surgery of either the internal carotid artery or the arteries of the lower limbs. Each patient had a thorough clinical examination, an ECG, and a dipyridamole-thallium-201 myocardial scan before operation. On the basis of results, they were divided into two groups: 20 patients with and 26 patients without chronic ischemic heart disease. Three major cardiac events were noted during or after a period of 1 month after surgery: There were two deaths due to cardiac ischemic events and one patient had postoperative unstable angina pectoris. These three patients were classified in the coronary group (NS). When the patients were classified on the basis of whether or not there was thallium redistribution on serial images after infusion of dipyridamole, 14 with redistribution and 32 without redistribution were noted. The three patients who had major cardiac events were in the former group (p less than 0.04). Our data suggest that patients in whom redistribution occurs have a high incidence of postoperative ischemic events. These patients should be considered for particular preoperative coronary care to avoid major postoperative cardiac events and to increase chances of survival.
1983年10月至1985年1月,46例患者(38例男性和8例女性;平均年龄60岁;范围37至83岁)接受了颈内动脉或下肢动脉的外周血管手术。每位患者在手术前均进行了全面的临床检查、心电图检查和双嘧达莫 - 铊 - 201心肌扫描。根据检查结果,他们被分为两组:20例患有慢性缺血性心脏病和26例未患慢性缺血性心脏病的患者。在手术后1个月内或术后1个月期间,记录到3起主要心脏事件:2例因心脏缺血事件死亡,1例患者术后发生不稳定型心绞痛。这3例患者被归类于冠心病组(无显著性差异)。当根据双嘧达莫输注后系列图像上是否存在铊再分布对患者进行分类时,发现14例有再分布,32例无再分布。发生主要心脏事件的3例患者在前一组(p小于0.04)。我们的数据表明,发生铊再分布的患者术后缺血事件发生率较高。应考虑对这些患者进行特殊的术前心脏护理,以避免术后重大心脏事件并增加生存机会。