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急性串联性椎基底动脉闭塞的血管内再通:七例病例系列并文献复习。

Endovascular revascularisation of acute tandem vertebrobasilar artery occlusion: seven case series with literature reviews.

机构信息

Department of Interventional Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Department of Neurology, Beijing Daxing Hospital, Capital Medical University, Beijing, China.

出版信息

Stroke Vasc Neurol. 2018 Jan 24;3(1):17-21. doi: 10.1136/svn-2017-000125. eCollection 2018 Mar.

DOI:10.1136/svn-2017-000125
PMID:29600003
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5870645/
Abstract

BACKGROUND

The outcome of acute ischaemic stroke due to tandem vertebrobasilar artery occlusion was poor. Endovascular revascularisation may be a positive approach for acute basilar artery occlusion combined with vertebral ostium stenosis or occlusion. We reported seven patients with acute vertebrobasilar tandem occlusion by using angioplasty or stenting for proximal lesion and thrombectomy for distal occlusion.

MATERIALS AND METHODS

Consecutive patients with acute tandem vertebrobasilar artery occlusion at two centres were included in this study. We retrospectively analysed the clinical, technical and functional outcomes of the patients.

RESULTS

From March 2016 to March 2017, seven patients were included. The mean age and National Institute of Health Stroke Scale score at admission was 57 years and 22, respectively. A reverse approach was used in five patients. The Thrombolysis in Cerebral Infarction score 2b-3 was acquired in all patients. There were no procedural complications. The modified Rankin Scale score was 1-2 for three patients and 4 for one patient at 3 months. Three patients died at 3 months of follow-up.

CONCLUSIONS

Endovascular revascularisation may be feasible for acute tandem vertebrobasilar artery occlusion, and more researches are needed.

摘要

背景

串联性椎基底动脉急性缺血性卒中的预后较差。血管内再通可能是急性基底动脉闭塞合并椎动脉口狭窄或闭塞的积极治疗方法。我们报道了 7 例采用血管成形术或支架置入治疗近端病变和血栓切除术治疗远端闭塞的急性椎基底动脉串联闭塞患者。

材料与方法

本研究纳入了两个中心的连续急性串联性椎基底动脉闭塞患者。我们对患者的临床、技术和功能结局进行了回顾性分析。

结果

2016 年 3 月至 2017 年 3 月,共纳入 7 例患者。入院时的平均年龄和美国国立卫生研究院卒中量表(NIHSS)评分分别为 57 岁和 22 分。5 例患者采用逆行入路。所有患者的血栓溶栓评分(TICI)均为 2b-3 级。无手术并发症。3 个月时,改良 Rankin 量表(mRS)评分 1-2 分的患者有 3 例,4 分的患者有 1 例。3 例患者在 3 个月随访时死亡。

结论

血管内再通可能对急性串联性椎基底动脉闭塞有效,需要进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a7b/5870645/f386d4003a39/svn-2017-000125f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a7b/5870645/47faeeb67c47/svn-2017-000125f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a7b/5870645/4bfd8a1aee7b/svn-2017-000125f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a7b/5870645/f386d4003a39/svn-2017-000125f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a7b/5870645/47faeeb67c47/svn-2017-000125f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a7b/5870645/4bfd8a1aee7b/svn-2017-000125f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a7b/5870645/f386d4003a39/svn-2017-000125f03.jpg

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