Why did VALIDATE-SWEDEHEART not validate the results of HORIZONS?
作者信息
Zeymer Uwe
机构信息
Klinikum Ludwigshafen, Institut für Herzinfarktforschung Ludwigshafen, Ludwigshafen, Germany.
出版信息
J Thorac Dis. 2018 Jan;10(1):35-37. doi: 10.21037/jtd.2017.11.126.
Abstract
摘要
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Why did VALIDATE-SWEDEHEART not validate the results of HORIZONS?为什么VALIDATE-SWEDEHEART研究没有验证HORIZONS研究的结果？
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本文引用的文献
1
Bivalirudin versus Heparin Monotherapy in Myocardial Infarction.比伐卢定与肝素单药治疗心肌梗死的比较。
N Engl J Med. 2017 Sep 21;377(12):1132-1142. doi: 10.1056/NEJMoa1706443. Epub 2017 Aug 27.
2
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Anticoagulation in coronary intervention.冠状动脉介入治疗中的抗凝。
Eur Heart J. 2016 Dec 1;37(45):3376-3385. doi: 10.1093/eurheartj/ehw061. Epub 2016 Mar 5.
4
An updated comprehensive meta-analysis of bivalirudin vs heparin use in primary percutaneous coronary intervention.关于比伐卢定与肝素在直接经皮冠状动脉介入治疗中应用的最新综合荟萃分析。
Am Heart J. 2016 Jan;171(1):14-24. doi: 10.1016/j.ahj.2015.10.006. Epub 2015 Oct 20.
5
Bivalirudin vs heparin with or without tirofiban during primary percutaneous coronary intervention in acute myocardial infarction: the BRIGHT randomized clinical trial.比伐卢定与肝素联合或不联合替罗非班用于急性心肌梗死患者经皮冠状动脉介入治疗的 BRIGHT 随机临床试验。
JAMA. 2015 Apr 7;313(13):1336-46. doi: 10.1001/jama.2015.2323.
6
Unfractionated heparin versus bivalirudin in primary percutaneous coronary intervention (HEAT-PPCI): an open-label, single centre, randomised controlled trial.普通肝素与比伐卢定在经皮冠状动脉介入治疗（HEAT-PPCI）中的应用：一项开放标签、单中心、随机对照试验。
Lancet. 2014 Nov 22;384(9957):1849-1858. doi: 10.1016/S0140-6736(14)60924-7. Epub 2014 Jul 4.
7
Bivalirudin is superior to heparins alone with bailout GP IIb/IIIa inhibitors in patients with ST-segment elevation myocardial infarction transported emergently for primary percutaneous coronary intervention: a pre-specified analysis from the EUROMAX trial.在因ST段抬高型心肌梗死而紧急转运接受直接经皮冠状动脉介入治疗的患者中，比伐卢定联合补救性糖蛋白IIb/IIIa抑制剂优于单用肝素：EUROMAX试验的一项预先指定分析。
Eur Heart J. 2014 Sep 21;35(36):2460-7. doi: 10.1093/eurheartj/ehu214. Epub 2014 May 21.
8
Bivalirudin started during emergency transport for primary PCI.比伐卢定在紧急转运行直接经皮冠状动脉介入治疗（PCI）期间开始使用。
N Engl J Med. 2013 Dec 5;369(23):2207-17. doi: 10.1056/NEJMoa1311096. Epub 2013 Oct 30.
9
Reduction in cardiac mortality with bivalirudin in patients with and without major bleeding: The HORIZONS-AMI trial (Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction).替奈普酶溶栓联合血管成形术与单独溶栓治疗急性心肌梗死的随机多中心临床试验
急性心肌梗死溶栓（TIMI）17 试验
急性 ST 段抬高型心肌梗死患者直接经皮冠状动脉介入治疗（直接 PCI）与溶栓后即刻补救性 PCI 随机临床试验
经皮冠状动脉介入治疗（PCI）后早期替罗非班对 ST 段抬高型心肌梗死患者的疗效和安全性的荟萃分析
J Am Coll Cardiol. 2014;63(1):15-20. doi: 10.1016/j.jacc.2013.09.027. Epub 2013 Oct 16.
10
Abciximab and heparin versus bivalirudin for non-ST-elevation myocardial infarction.阿昔单抗和肝素与比伐卢定用于非 ST 段抬高型心肌梗死。
N Engl J Med. 2011 Nov 24;365(21):1980-9. doi: 10.1056/NEJMoa1109596. Epub 2011 Nov 13.
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