Kaya Mahmut, Ozbek Zeynep, Yaman Aylın, Durak Ismet
Department of Ophthalmology, Dokuz Eylul University, Izmir, Turkey.
Int J Ophthalmol. 2012;5(1):108-12. doi: 10.3980/j.issn.2222-3959.2012.01.22. Epub 2012 Feb 18.
To evaluate the long-term results and complications of ahmed glaucoma valve (AGV) implantation in refractory glaucoma.
A retrospective review of 13 patients (13 eyes) with refractory glaucoma who underwent AGV implantation and had a minimum follow-up of 18 months was performed. All patients underwent a complete ophthalmologic examination and intraocular pressure (IOP) measurement before surgery and at 1 month, 3 months, 6 months, 1 year after surgery and yearly afterwards. Complications and the number of antiglaucoma medications needed were recorded.
Mean age was 27.3±16.0 years. All eyes (100%) had at least one prior incisional surgery. Mean follow-up was 61.3±30.8 months. IOP was reduced from a mean of 35.0 ±7.0mmHg to 18.2±7.9mmHg at 12 months and to 17.0±4.1mmHg at 96 months (P<0.05) with a lower number of medications from baseline, 76.9% patients required additional procedures to achieve the success criteria set by previously published series. The most common complications were encapculated cyst formation in eight eyes (61.5 %) and tube exposure in four eyes (30.8%).
Encapsulated cyst formation was the most common complication which hindered succesful IOP control after AGV implant insertion for refractory glaucoma. Despite cyst excision with anti-fibrotic agents, successful IOP reduction was not achieved in 76.9% of the patients without antiglaucoma medication.
评估艾哈迈德青光眼引流阀(AGV)植入术治疗难治性青光眼的长期疗效及并发症。
回顾性分析13例(13眼)难治性青光眼患者,这些患者接受了AGV植入术,且至少随访18个月。所有患者在手术前、术后1个月、3个月、6个月、1年及之后每年均接受全面的眼科检查及眼压(IOP)测量。记录并发症及所需抗青光眼药物的数量。
平均年龄为27.3±16.0岁。所有患眼(100%)均至少接受过一次既往切开手术。平均随访时间为61.3±30.8个月。眼压在12个月时从平均35.0±7.0mmHg降至18.2±7.9mmHg,在96个月时降至17.0±4.1mmHg(P<0.05),且药物使用数量较基线减少,76.9%的患者需要额外的手术以达到既往发表系列所设定的成功标准。最常见的并发症是8眼(61.5%)出现包裹性囊肿形成,4眼(30.8%)出现引流管暴露。
包裹性囊肿形成是最常见的并发症,阻碍了AGV植入术治疗难治性青光眼后眼压的成功控制。尽管采用抗纤维化药物切除囊肿,但76.9%未使用抗青光眼药物的患者眼压未能成功降低。