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一名静脉药物滥用者髋部感染性关节炎的迟发及隐匿表现

Late and Vague Presentation of Septic Arthritis of Hip in a IVDrug Abuser.

作者信息

Raghupathi Anantha Krishnan, Joshi Avinash

机构信息

Department of Orthopaedics, Southend University Hospital, Southend - On-Sea, United Kingdom.

Department of Orthopaedics, Princess Elizabeth Hospital, St Andrews, Guernsey, United Kingdom.

出版信息

J Orthop Case Rep. 2017 Nov-Dec;7(6):13-15. doi: 10.13107/jocr.2250-0685.928.

Abstract

INTRODUCTION

Septic arthritis of the hip is a rare entity in acute presentation of hip pain in adults. Even though hip is the second most commonly affected joint, adult patients with septic arthritis not related to a surgical procedure represent <0.00001% of total acute admissions.

CASE REPORT

We present a 32-year-old female intravenous drug abuser, positive for Hepatitis B and C who had started to inject her femoral veins 2 years ago. She presented with a 10 weeks history of radiating pain in the leg which was full, constant and diffuse in nature with hip stiffness. She was treated for sciatica by her GP. She had later visited A and E twice (5 and 8 weeks) and was again treated symptomatically. She started to have increasing pain, hip stiffness, reduced mobility, and developed swelling of both legs extending upto groin medially. The patient was apyrexial throughout these visits. She did not have back/buttock pain. X-ray showed loss of joint space with evidence of articular surface destruction. Ultrasound showed no fluid collection inside the joint and deep vein thrombosis was ruled out. Hip joint was aspirated, and cultures grew Staphylococcus aureus from the aspirate. Flucloxacillin and fucidin were started as per hospital protocol. Skin traction was applied for pain relief with active hip movements as possible. Magnetic resonance imaging demonstrated complete joint destruction post- infective septic arthritis. After 8 weeks of antibiotics, inflammatory markers improved. Follow up X-ray showed complete ankylosis of hip joint, severe restriction ofhip movements and was allowed weight bearing as possible.

CONCLUSION

Risk of septic arthritis should always be considered in mind when dealing with these cohorts of patients. Threshold for septic arthritis should be much lower especially in patients with complicated history, current or ex-drug abuser and presenting with vague symptoms. Early diagnosis, detection of organisms, specific targeted antibiotics, and joint wash out with a future consideration of total hip arthroplasty when the infection has settled will help patients resume their normal function.

摘要

引言

成人急性髋部疼痛中,化脓性髋关节炎是一种罕见疾病。尽管髋关节是第二常见的受累关节,但与手术无关的成人化脓性关节炎患者占急性入院总数的比例不到0.00001%。

病例报告

我们报告一名32岁女性静脉吸毒者,乙肝和丙肝检测呈阳性,2年前开始注射股静脉。她出现腿部放射性疼痛10周,疼痛性质为饱满、持续且弥漫,伴有髋关节僵硬。她的全科医生按坐骨神经痛对其进行了治疗。她后来两次前往急诊室(分别在5周和8周时),再次接受了对症治疗。她开始出现疼痛加剧、髋关节僵硬、活动能力下降,并出现双腿肿胀,内侧延伸至腹股沟。在这些就诊过程中,患者体温正常。她没有背部/臀部疼痛。X线显示关节间隙变窄,有关节面破坏的迹象。超声显示关节内无积液,排除了深静脉血栓形成。对髋关节进行了穿刺抽吸,培养物从抽吸物中培养出金黄色葡萄球菌。按照医院方案开始使用氟氯西林和夫西地酸。应用皮肤牵引以缓解疼痛,并尽可能进行髋关节主动活动。磁共振成像显示感染后化脓性关节炎导致关节完全破坏。使用抗生素8周后,炎症指标有所改善。随访X线显示髋关节完全强直,髋关节活动严重受限,允许尽可能负重。

结论

在处理这类患者群体时,应始终考虑化脓性关节炎的风险。尤其是对于有复杂病史、当前或既往吸毒者且症状不明确的患者,化脓性关节炎的诊断阈值应更低。早期诊断、病原体检测、针对性抗生素治疗以及关节冲洗,在感染得到控制后考虑全髋关节置换术,将有助于患者恢复正常功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/916f/5868874/fee7c62e5e97/JOCR-7-13-g001.jpg

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