Department of Rheumatology, West Middlesex Hospital, London, UK.
Department of Radiology, West Middlesex Hospital, London, UK.
Mod Rheumatol Case Rep. 2021 Jul;5(2):387-390. doi: 10.1080/24725625.2020.1857021. Epub 2021 Jan 18.
Polyarticular septic arthritis is an underappreciated clinical entity. Pre-existing joint diseases, such as osteoarthritis and rheumatoid arthritis have been shown to be risk factors for septic arthritis. However, there is a paucity of data in the literature regarding the risk of septic arthritis in those patients with enteropathic arthritis. Here, we describe the case of a 47-year-old female with a background history of ulcerative colitis who presented with difficulty mobilising and pain in the hips associated with lethargy, fever and a significant inflammatory response. After an investigative process, she was newly diagnosed with enteropathic arthritis, complicated at presentation, by bilateral septic arthritis of the hips, based on progressive radiological destruction and a joint aspirate that grew . After treatment with antibiotics and steroids, her pain and mobility significantly improved, and she was discharged with a plan for an elective hip replacement and to commence disease-modifying therapy with sulfasalazine. This case reminds us that we must have a high index of suspicion to diagnose septic arthritis in those who present feverish and unwell with joint pain, even in those who present with multiple joint involvement. Furthermore, it describes a rare occurrence of bilateral septic arthritis of the hips occurring in a patient with enteropathic arthritis, which unlike osteoarthritis and rheumatoid arthritis, is not well described in the literature as a risk factor for septic arthritis.
多关节化脓性关节炎是一种被低估的临床实体。已经表明,先前存在的关节疾病,如骨关节炎和类风湿关节炎是化脓性关节炎的危险因素。然而,关于患有肠炎性关节炎的患者发生化脓性关节炎的风险,文献中数据很少。在这里,我们描述了一位 47 岁女性的病例,她有溃疡性结肠炎病史,出现髋关节活动困难和疼痛,伴有乏力、发热和明显的炎症反应。经过一系列检查,她被新诊断为肠炎性关节炎,表现为双侧髋关节化脓性关节炎,影像学检查显示进行性破坏,关节抽吸物培养出 。经过抗生素和类固醇治疗,她的疼痛和活动能力显著改善,出院时计划进行髋关节置换术,并开始使用柳氮磺胺吡啶进行疾病修饰治疗。这个病例提醒我们,对于那些出现发热、关节疼痛和不适的患者,即使存在多个关节受累,我们也必须高度怀疑化脓性关节炎的诊断。此外,它描述了一种罕见的双侧髋关节化脓性关节炎发生在肠炎性关节炎患者中,与骨关节炎和类风湿关节炎不同,它在文献中并未被很好地描述为化脓性关节炎的危险因素。