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组织芯片在食管腺癌中的应用

Application of Tissue Microarray in Esophageal Adenocarcinoma.

作者信息

Saremi Nassim, Lam Alfred K

机构信息

Cancer Molecular Pathology of School of Medicine, Griffith University, Gold Coast, Australia.

出版信息

Methods Mol Biol. 2018;1756:105-118. doi: 10.1007/978-1-4939-7734-5_10.

Abstract

Tissue microarray technology could allow immunohistochemical staining or in situ hybridization on hundreds of different tissue samples simultaneously. It allows faster analysis and considerably reducing costs incurred in staining. The technique also provides a high-throughput analysis of multiple tissues for the different types of research. In the literature, many researches of esophageal adenocarcinoma use tissue microarray to enhance the output. In this chapter, we have a brief overview of tissue microarray technologies, the advantages and disadvantages of tissue microarray, and related troubleshootings.

摘要

组织芯片技术能够同时对数百个不同的组织样本进行免疫组织化学染色或原位杂交。它能实现更快的分析,并大幅降低染色成本。该技术还为不同类型的研究提供了对多种组织的高通量分析。在文献中,许多食管腺癌的研究都使用组织芯片来提高产出。在本章中,我们将简要概述组织芯片技术、组织芯片的优缺点以及相关故障排除方法。

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