食管腺癌的组织病理学评估

Histopathological Assessment for Esophageal Adenocarcinoma.

作者信息

Lam Alfred K

机构信息

Cancer Molecular Pathology of School of Medicine, Griffith University, Gold Coast, Australia.

出版信息

Methods Mol Biol. 2018;1756:67-76. doi: 10.1007/978-1-4939-7734-5_6.

DOI:10.1007/978-1-4939-7734-5_6

PMID:29600360

Abstract

In the World Health Organization (WHO) classification, adenocarcinoma of esophagus comprises preinvasive type (dysplasia), adenocarcinoma, adenoid cystic carcinoma, adenosquamous carcinoma, and mucoepidermoid carcinoma. For adenocarcinoma, it is important to determine the grading of the cancer and histological variants such as signet ring adenocarcinoma. In the current day management of esophageal adenocarcinoma by neoadjuvant therapy, the histology of the cancer and the lymph nodal status may change after the therapy. Tumor regression grading systems could be used to assess the response to the neoadjuvant therapy in esophageal adenocarcinoma.

摘要

在世界卫生组织（WHO）的分类中，食管腺癌包括浸润前型（发育异常）、腺癌、腺样囊性癌、腺鳞癌和黏液表皮样癌。对于腺癌，确定癌症的分级以及组织学变体（如印戒腺癌）很重要。在当前通过新辅助治疗管理食管腺癌的过程中，治疗后癌症的组织学和淋巴结状态可能会发生变化。肿瘤消退分级系统可用于评估食管腺癌对新辅助治疗的反应。