马齿苋提取物的肝脏保护作用：综述
The Hepato-protective Effects of Portulaca oleracea L. extract: Review.
作者信息
Farkhondeh Tahereh, Samarghandian Saeed, Azimi-Nezhad Mohsen, Hozeifi Soroush
机构信息
Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Noncommunicable Disease Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran.
出版信息
Curr Drug Discov Technol. 2019;16(2):122-126. doi: 10.2174/1570163815666180330142724.
BACKGROUND
Portulaca oleracea L. (Purslane) has been used in traditional medicine against hepatic injury, although its actual efficacy has not been fully understood. The present study aimed to critically review the recent literature data from 1990 to 2017 regarding the hepato-protective effects of Portulaca oleracea L. and its underlying mechanisms.
METHODS
Online literature resources were checked using different search engines such as Medline, PubMed, Iran Medex, Scopus, and Google Scholar to identify articles, editorials, and reviews about antidotal effects of Portulaca oleracea L. against hepatotoxic agents.
RESULTS
Few studies have indicated that Portulaca oleracea L. shows protective effects against hepatotoxic agents. However, due to lack of information in humans, more studies are needed to confirm the efficacy of Portulaca oleracea L. as a hepato-protective agent.
CONCLUSION
The study found that Portulaca oleracea L. may be effective on hepatotoxicity by modulating oxidative stress and inflammation.
背景
马齿苋在传统医学中被用于治疗肝损伤，但其实际疗效尚未完全明确。本研究旨在批判性地回顾1990年至2017年期间关于马齿苋保肝作用及其潜在机制的最新文献数据。
方法
使用不同的搜索引擎，如Medline、PubMed、Iran Medex、Scopus和谷歌学术，检索在线文献资源，以识别有关马齿苋对肝毒性药物解毒作用的文章、社论和综述。
结果
少数研究表明马齿苋对肝毒性药物具有保护作用。然而，由于缺乏人体研究信息，需要更多研究来证实马齿苋作为保肝剂的疗效。
结论
该研究发现马齿苋可能通过调节氧化应激和炎症对肝毒性发挥作用。
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